Large scale synthesis of twelve member diazamonocyclic compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...

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540460, 540469, 558 81, C07D27308

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active

049008188

ABSTRACT:
A process is disclosed for synthesizing large quantities of a compound of formula I ##STR1## wherein a solution of a compound of formula II ##STR2## is mixed with a solution of a compound of formula III ##STR3## under suitable process conditions, and wherein A, same or different, is N--R, O, S, CRR' or P(O)R, and R and R' are hydrogen, alkyl, alkylidene, aryl, tosyl, allyl or benzyl, and B is O.
Compounds of formula I may be reduced to form an azacorand of formula IV ##STR4## wherein K and L, same or different, are N--R, O, S, CRR', or P(O)R, and R and R' are hydrogen, alkyl, alkylidene, aryl, tosyl, allyl or benzyl.
Also disclosed in a compound of formula IV synthesized in accordance with the above procedure wherein K and L are not both O or S.

REFERENCES:
patent: 4845212 (1989-07-01), Czech

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