Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Patent
1994-12-22
1997-02-04
Kight, John
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
568436, 568437, C07C24900, C07C 4500, C07C 4590
Patent
active
055999883
ABSTRACT:
A novel process for producing chiral hydroxylamines for use as intermediates to make chiral hydroxyureas, which process comprises a tandem condensation-cyclization reaction between a dimethylsulfoxoniurn methylide and an appropriately substituted nitrone bearing a D- or L- mannose chiral auxiliary to yield a compound of Formula (I) as claimed herein.
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Crane L. Eric
Dinner Dara L.
Kight John
Lentz Edward T.
SmithKline Beecham Corporation
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