Large granular lymphocyte leukemia associated virus

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se

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435372, C12N 508, C12N 510, C12N 700

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active

058917233

ABSTRACT:
A large granular lymphocyte (LGL) leukemia related virus has been isolated and characterized from patients having LGL leukemia. The virus appears to be related to the family of retroviruses including HTLV-I, HTLV-I and Bovine Leukemia Virus. Nucleic acid sequences of the virus are presented.

REFERENCES:
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patent: 5239056 (1993-08-01), Portetellie et al.
patent: 5521083 (1996-05-01), Loughran et al.
Fan, N., et al., "Infection of Peripheral Blood Mononuclear Cells and Cell Lines by Cell-Free Human T-Cell Lymphoma/Leukemia Virus Type I," J. Clin. Microbiol. 30(4):905-910 (1992).
Loughran, Jr., T.P., et al., "Detection of Human T-Cell Leukemia/Lymphoma Virus, Type II, in a Patient with Large Granular Lymphocyte Leukemia," Blood 80(5):1116-1119 (1992).
Loughran, Jr., T.P., "Clonal Diseases of Large Granular Lymphocytes," Blood 82(1):1-14 (1993).

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