Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1987-04-15
1989-12-26
Teskin, Robin
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
435255, 435256, 435320, 435912, 435 692, 435 94, 935 28, 935 55, 935 56, 935 67, C12N 1500, C12N 500, C12N 700
Patent
active
048898066
ABSTRACT:
A large DNA cloning system is disclosed which is based on yeast artificial chromosomes. Cloning vectors are disclosed which allow the cloning of large segments of greater than 50 kb of exogenous DNA. The cloning vector comprises DNA sequences of an autonomous replication sequence, a centromere, a selectable yeast marker, two sequences that seed telomere function in vivo, and a cloning site within an interruptible yeast gene for insertion of the exogenous DNA segments.
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Burke David T.
Olson Maynard V.
Meyer Scott J.
Teskin Robin
Washington University
Williams, Jr. James W.
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