Lanthanide chelate conjugated oligonucleotides

Details Lanthanide chelate conjugated oligonucleotides Lanthanide chelate conjugated oligonucleotides

1997-03-05

1999-09-21

Houtteman, Scott W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 2433, 536121, 536101, C07H 2104

Patent

active

059556013

ABSTRACT:
Rare earth chelate-conjugated oligonucleotides useful in nucleic acid hybridization assays and for generating chelate-labelled probes of any desired sequence are disclosed. The particular class of chelates utilized exhibit an unusually high efficiency of rare earth element capture, correlated with emission of a high level of signal in time-resolved fluorescence spectroscopy compared to other structurally related chelate compounds.

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