Laminin a chain polypeptides from the carboxy terminal globular

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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424422, 424423, 514 1, 514 2, 514 8, 530326, 530327, 530395, 623 4, 623 6, A61F 216, A61F 206, A61F 3710, C07K 504

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052663280

ABSTRACT:
Polypeptides derived from the G domain of the A chain of laminin and having sequences of at least about 5 amino acids, and which exhibit heparin/glycosaminoglycan binding, cell adhesion and cell spreading capacity are described.
Medical devices such as prosthetic implants, percutaneous devices and cell culture substrates coated with a composition including the described polypeptides are also provided.

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