Laminin a chain deduced amino acid sequence, expression vectors

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Stent structure

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

623 11, 623 66, 623 12, 514 13, 514 14, 514 15, 530326, 530327, A61F 206, A61F 202

Patent

active

052116573

ABSTRACT:
The present invention relates to peptides and derivatives thereof having laminin-like activity. The invention further relates to pharmaceutical compositions containing these peptides, to antibodies effective against these peptides, and to vectors containing a DNA sequence of cDNA coding for the A chain of laminin. The peptides of the invention may be used to treat diseases such as cancer.

REFERENCES:
patent: 4340581 (1982-07-01), Timpl
patent: 4497799 (1985-02-01), Yoshizumi et al.
patent: 4565789 (1986-01-01), Liotta et al.
patent: 4609629 (1986-09-01), Timpl
patent: 4614517 (1986-09-01), Ruoslahti et al.
patent: 4642293 (1987-02-01), Chung
patent: 4714643 (1987-12-01), Shoyab et al.
patent: 4870160 (1989-09-01), Charonis et al.
patent: 4876332 (1989-10-01), Tsilibary et al.
Graf et al, "A Pentapeptide from the Laminin B1 Chain Mediates Cell Adhesion and Binds the 67 000 Laminin Receptor", Biochemistry, Nov. 3, 1987, pp. 6896-6900.
Iwamoto et al, "Synthetic Pentapeptide From the B1 Chain of Laminin Promotes a B16F10 Melanoma Cell Migration", Journal of Cellular Physiology, vol. 134, pp. 287-291 (1988).
Terranova, "Regulation of Cell Attachment and Cell Number by Fibronectin and Laminin", Journal of Cellular Physiology 127:473-479 (1986).
Barsky, Laminin Molecular Domains which Alter Metastasis in a Murine Model J. Clin. Invest., vol. 74, Sep. 1984, pp. 843-848.
Graf, "Identification of an Amino Acid Sequence in Laminin Mediating Cell Attachment, Chemotaxis, and Receptor Binding", Cell, vol. 48, pp. 989-996.
Sasaki, Sequence of the cDNA Encoding the Laminin B1 Chain Reveals a Multi-Domain Protein Containing Cystein-Rich Repeat, Proc. Natl. Acad. Sci., vol. 84, pp. 935-939.
Iwamoto et al, "YIGSR, a Synthetic Laminin Pentapeptide, Inhibits Experimental Metastasis Formation", Science, vol. 238, pp. 1132-1134.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Laminin a chain deduced amino acid sequence, expression vectors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Laminin a chain deduced amino acid sequence, expression vectors , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Laminin a chain deduced amino acid sequence, expression vectors will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-801133

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.