Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1998-04-14
2000-03-07
Lankford, Jr., Leon B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
424422, 435325, 435366, 435 41, 435402, 514 2, 514 12, 514801, 530350, 530395, 623 11, 623 15, A61K 3800, A61F 202, A61F 210, A61F 1300
Patent
active
060340681
ABSTRACT:
A trans-epithelial appliance or shaped article coated with laminin 5. Laminin 5 stimulates cell attachment and may be comprise an insoluble or soluble cell matrix. The appliance will be useful for reducing inflammation and/or infection at the site of entry of the appliance. The appliance may also be used to stimulate gum junctional epithelium adhesion in the treatment of, for example, gingivitis and periodontitis.
REFERENCES:
patent: 4870160 (1989-09-01), Charonis et al.
patent: 5092885 (1992-03-01), Yamada et al.
patent: 5266328 (1993-11-01), Skubitz et al.
patent: 5422264 (1995-06-01), Quaranta et al.
patent: 5489300 (1996-02-01), Capecchi et al.
patent: 5510263 (1996-04-01), Quaranta et al.
patent: 5541106 (1996-07-01), Jones
patent: 5585267 (1996-12-01), Jones et al.
patent: 5656593 (1997-08-01), Kuberasampath et al.
patent: 5672361 (1997-09-01), Halberstadt et al.
patent: 5770448 (1998-06-01), Jones et al.
Haapasalmi et al. Am. J. Pathol. vol. 147 (1), pp. 193-206, 1995.
W.G. Carter, et al., Epiligrin, A New Cell Adhesion Ligand For Intergrin .alpha.3.beta.1 in Epithelial Basement Membranes, Cell,, 65:599-610, (1991).
Champliaud et al., J. Cell Biol., 132(6):1189-1198, Abstract, Mar. 1996.
K. Garrison, et al., Drosophila Laminin A Chain Sequence, Interspecies Comparison, and Domain Structure of a Major Carboxyl Portion, J. Biol. Chem., 266(34):22899-22904 (1991).
Y. Hieda, et al., Identification of a New Hemidesmosomal Protein, HD1: A Major, High Molecular Mass Component of Isolated Hemidesmosomes, J. Cell Biol., 116(6):1497-1506 (1992).
B. Hsi, et al., Monoclonal Antibody GB.sub.3 6 Raised Against Human Trophoblast Recognizes a Novel Epithelial Antigen, Placenta,, 8:209-217 (1987).
K. Izumi, et al., In Vitro Induction of Ornithine Decarboxylase in Urinary Bladder Carcinoma Cells, Cancer Research, 41:405-409 (1981).
P. Kallunki, et al., A Truncated Laminin chain Homologous to the B2 Chain: Structure, Spatial Expression, and Chromosomal Assignment, J. Cell Biol, 119(3):679-693, (1992).
M. Langhofer, et al., The Matrix Secreted by 804G Cells Contains Laminin-Related Components that Participate in Hemidesmosome Assembly in Vitro, J. Cell Science, 105:753-764, (1993).
Nishiyama, et al., Annual Meeting Soc. Invest. Dermatol.,, Abstract May 1995.
Nishiyama, et al., 34th Annual Meeting Am. Soc. Cell Biol., Abstract 1994.
K.S. Riddelle, et al., Formation of Hemidesmosomes in Vitro By a Transformed Rat Bladder Cell Line, J. Cell Biol., 112(1):159-168 (1991).
K.S. Riddelle, et al., Hemidesmosomes in the Epithelial Cell Line 804G: Their Fate During Wound Closure, Mitosis and Drug Induced Reorganization of the Cytoskeleton, J. Cell Science, 103:475-490 (1992).
P. Rousselle, et al., Kalinin: An Epithelium-Specific Basement Membrane Adhesion Molecule that is a Component of Anchoring Filaments, IJ. Cell Biol. 114(3):567-576 (1991).
L.A. Staehelin, Structure and Function of Intercellular Junctions, Dept. of Molecular, Cellular and Developmental Biology, Univ. of Colorado, Boulder, Colorado, 191-283 (1974).
P. Verrando, et al., The New Basement Membrane Antigen Recognized by the Monoclonal Antibody GB3 is a Large Size Glycoprotein: Modulation of its Expression by Retinoic Acid, Biochimica et Biophysica Acta, 942:45-56 (1988).
Desmos Incorporated
Lankford , Jr. Leon B.
Tate Christopher R.
LandOfFree
Laminin 5 for periodontal treatment does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Laminin 5 for periodontal treatment, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Laminin 5 for periodontal treatment will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-363192