Laminin 5 for growth of pancreatic islet cells

Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Digestive system

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424 937, 424562, 435350, 435351, 435352, 435363, 435366, 435402, 514 3, A61K 3539, A61K 3828, C12N 506, C12N 508

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active

056723610

ABSTRACT:
A method of expanding the number of pancreatic islet cells for transplantation. Fetal islet cells are cultured in the presence of laminin 5 extracellular matrix, resulting in a significant increase in cell number after passaging in culture. The expanded islet cells contain insulin and respond to glucose challenge.

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