Lactulose purification process

Sugar – starch – and carbohydrates – Processes – Carbohydrate manufacture and refining

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C13D 312

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active

045655820

ABSTRACT:
A process for purifying lactulose from other carbohydrates, in particular from lactose and galactose, by passing a lactulose syrup through one or more columns containing a bifunctionalized boron resin of the type: ##STR1## in which .circle.P is a polyacrylic or polystyrene polymer matrix and R, R.sup.1, R.sup.2, R.sup.3, X are as defined in the text.
By passing the lactulose solution containing carbohydrate impurities through a boron resin (I) of polyacrylic matrix, the lactulose is selectively retained and is subsequently released by elution with an acid solution.
The small quantity of galactose which may still be contained in the lactulose-enriched solution can be removed by passing said solution through a boron resin (I) of polystyrene matrix, which selectively retains the galactose.

REFERENCES:
patent: 3505309 (1970-04-01), Carubelli
patent: 3546206 (1970-12-01), Guth et al.
patent: 3562012 (1971-02-01), Reinicke et al.
patent: 3716408 (1973-02-01), Nagasawa et al.
patent: 3816174 (1974-06-01), Nagasawa et al.
patent: 3864166 (1975-02-01), Barker et al.
Yurkevich et al., "Study of the Interaction of Polyols with Polymers Containing N-Substituted [(4-Boronophenyl)Methyl]-Ammonio Groups", Carbohydrate Research, 43 (1975), pp. 215-224.

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