Lactonyl esters of penicillins

Details Lactonyl esters of penicillins Lactonyl esters of penicillins

1976-08-05

1977-07-19

Schwartz, Gerald A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260243C, 424271, 424246, C07D49944, C07D49946, C07D49948, C07D49964

Patent

active

040368297

ABSTRACT:
Lactonyl esters of Penicillins of the formula ##STR1## WHEREIN R.sup.1 is an antibacterially active penicillin-completing side chain; R is hydrogen, methyl or phenyl; and Ra, Rb, Rc, Rd are hydrogen, lower alkyl, lower alkoxy, halo, and nitro, provided that when R is hydrogen and R.sup.1 is D-.alpha.-aminophenylacetamido and Ra, Rb, Rc, and Rd are not all hydrogen are disclosed to possess antibacterial properties.

REFERENCES:
patent: 2985648 (1961-05-01), Doyle et al.
patent: 3641001 (1972-02-01), Love et al.
patent: 3647783 (1972-03-01), Pirie
patent: 3697507 (1972-10-01), Frederiksen et al.
patent: 3860579 (1975-01-01), Ferres et al.

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