Lactone stable formulation of camptothecin and methods for uses

Details Lactone stable formulation of camptothecin and methods for uses Lactone stable formulation of camptothecin and methods for uses

1994-05-09

1997-01-28

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3144

Patent

active

055978290

ABSTRACT:
Camptothecin (CPT) an anticancer drug is poorly soluble in water. This invention overcomes this limitation by teaching novel pharmaceutically acceptable lactone stable CPT formulations for the direct administration of CPT to human subjects with cancer. The claimed invention also describes novel dosages, schedules, and routes of administration of the lactone stable CPT formulations to patients with various forms of cancer.

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