Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – From carboxylic acid or derivative thereof
Reexamination Certificate
2007-04-17
2007-04-17
Boykin, Terressa (Department: 1711)
Synthetic resins or natural rubbers -- part of the class 520 ser
Synthetic resins
From carboxylic acid or derivative thereof
C215S011100, C428S035700, C514S212010, C514S212020, C528S354000
Reexamination Certificate
active
11114452
ABSTRACT:
The present invention pertains to biodegradable polymers comprising a non-polymerizable lactone, biodegradable compositions comprising the polymer and a therapeutic agent, the use of the compositions for the sustained release of therapeutic agents, wherein the therapeutic agent is reversibly immobilized on the polymer matrix using ionic complexation between the latent carboxylic groups present on the lactone bearing polymer matrix and a cationic group on the therapeutic agent.
REFERENCES:
patent: 4675189 (1987-06-01), Kent et al.
patent: 4767628 (1988-08-01), Hutchinson
patent: 4943382 (1990-07-01), Gutierrez et al.
patent: 5256765 (1993-10-01), Leong
patent: 0 440 108 (1991-08-01), None
patent: 2 145 422 (1985-03-01), None
patent: WO 93/20126 (1993-10-01), None
Hashimoto, K. et al., “Macromolecular Synthesis from Saccharic Lactones . . . ”, J. of Poly. Science: Part A: Polymer Chem., vol. 33, pp. 1495-1503, (1995).
Hutchinson, F.G. et al., “Biodegradable Polymer Systems for the Sustained Release of PolyPeptides”, J. of Controlled Release, vol. 13, pp. 279-294, (1990).
Johns, D. B. et al., “Lactones”, Ring-Opening Polymerization, vol. 1, Chapter 7, pp. 461-521, edited by K. J. Ivin & T. Saegusa, Elsevier Applied Science Publishers, London & New York, (1984).
O'Donnell, P.B. et al., “Preparation of Microspheres by the Solvent Evaporation Technique”, Adv. Drug Delivery Reviews, vol. 28, pp. 25-42, (1997).
Sintzel, M. B. et al., “Synthesis and Characterization of Self-Catalyzed poly(ortho ester)”, Biomaterials, vol. 19, pp. 791-800, (1998).
Vandorpe, J. et al., “Biodegradable Polyphosphazeres for Biomedical Applications”, Handbook of Biodegradable Polymers, pp. 161-182, Chapter 9, edited by A. J. Domb, J. Kost and D. M. Wiseman, Harwood Academic Publishers, Australia et al., (1997).
Boykin Terressa
Feeney Alan F.
Fish & Richardson
Societe de Conseils de Recherches et d'Applications Scientifique
Uhm Tony K.
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