Lactone bearing absorbable polymers

Details Lactone bearing absorbable polymers Lactone bearing absorbable polymers

2005-10-18

2005-10-18

Page, Thurman K. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S484000, C424S486000, C424S422000, C514S772300

Reexamination Certificate

active

06955822

ABSTRACT:
The present invention pertains to biodegradable polymers comprising a non-polymerizable lactone, biodegradable compositions comprising the polymer and a therapeutic agent the use of the compositions for the sustained release of therapeutic agents, wherein the therapeutic agent is reversibly immobilized on the polymer matrix using ionic complexation between the latent carboxylic groups present on the lactone bearing polymer matrix and a cationic group on the therapeutic agent.

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