Lactoferrin hydrolyzate for use as an antibacterial agent and as

Details Lactoferrin hydrolyzate for use as an antibacterial agent and as Lactoferrin hydrolyzate for use as an antibacterial agent and as

1991-12-09

1995-02-14

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

426656, 426657, 514 2, 514 12, 514 21, 530395, 530407, 435 681, C07K 310, C07K 112

Patent

active

053896114

ABSTRACT:
Lactoferrin hydrolyzates, having a decomposition rate between 6%-20% as measured by formol titration, for use as an antibacterial agent, and which have remarkably more potent activity than unhydrolyzed lactoferrin; and lactoferrin hydrolyzates, having a decomposition rate between 4-50% as measured by formol titration, for use as a tyrosinase inhibition agent, are obtainable by conventional methods for hydrolysis with acids or enzymes, and are stable to heating.

REFERENCES:
patent: 4668771 (1987-05-01), Kawakami et al.
patent: 4791193 (1988-12-01), Okonogi et al.
patent: 4918008 (1990-04-01), Gauri
patent: 4997914 (1991-03-01), Kawakami et al.
patent: 5214028 (1993-05-01), Tomita et al.
Suzuki et al., Agric. Biol. Chem., vol. 53(6), pp. 1705-1706 (1989).
Spik et al., Biochimie, vol. 70 (1988), pp. 1459-1469.
Stryer, "Biochemistry," 3rd Ed. (1988), pp. 202-211.
Tomita et al, J. Dairy Sci. 74:1437-1442 (1991).

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