Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1997-05-30
2000-04-18
Krass, Frederick
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
424 9345, 4242341, 4242461, 435170, 4352529, 4353171, 435803, 435820, 435853, 435854, 435855, 435856, 435857, A61K 3574
Patent
active
06051552&
ABSTRACT:
The present invention is directed towards isolated lactobacillus biosurfactants and the process for producing same. The present invention is also directed to methods for preventing urogenital infection in mammals using the isolated lactobacillus biosurfactant. The present invention is further directed to methods of inhibiting microbial biofilm formation using the isolated lactobacillus biosurfactant to prevent the formation of bacterial biofilms, and to displace adherent biofilm-forming bacteria from surfaces.
REFERENCES:
Hawthorne, Lesleyann et al. "The effect of protein and urine on uropathogen adhesion to polymer substrata," Journal of Biomedical Materials Research, 1990, 24, 1325-1332.
Reid, Gregor et al. "Adhesion of Lactobacilli to Polymer Surfaces in Vivo and in Vitro," Microbial Ecology, 1988, 16, 241-251.
Reid, Gregor et al. "Effect of Bacterial, Urine and Substratum Surface Tension Properties on Bacterial Adhesion to Biomaterials," Biofouling, 1991, 4, 171-176.
Reid, Gregor et al. "Microbial adhesion to biomaterials and infections of the urogenital tract," Colloids and Surfaces B: Biointerfaces, 1994, 2, 377-385.
Reid, Gregor et al. "Adhesion of lactobacilli to urinary catheters and diapers: Effect of surface properties," Journal of Biomedical Materials Research, 1994, 28 731-734.
Velraeds, Martine M.C. et al. "Interference of Lactobacilli and Lactobacillus Biosurfactants in Uropathogen Adhesion," London, Ontario, 1995, (live presentation of experiment results).
Velraeds, Martine M.C. et al. "Physicochemical and biochemical characterization of biosurfactants released by Lactobacillus strains," Colloids and Surfaces B: Biointerfaces, 1996, 8, 51-61.
Velraeds, Martine M.C. et al. "Inhibition of Initial Adhesion of Uropathogenic Enteroccus faecalis by Biosurfactants from Lactobacillus Isolates," Applied and Environmental Microbiol., 1996, 62, 1958-1963.
Bruce Andrew W.
Busscher Henk J.
Reid Gregor
Van der Mei Henny C.
Krass Frederick
Urex Biotech, Inc.
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