Lactobacillus living body activating Lactobacillus...

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

Reexamination Certificate

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C424S093450

Reexamination Certificate

active

07863033

ABSTRACT:
There has been effort to develop a lactobacillus that would be useful as a probiotic, and to develop a lactobacillus which would colonize and proliferate in lesions of infection, eliminating the causal bacteria.This problem was resolved by developing aLactobacillus caseispecies having the following key properties. (1) The species can be grown in the presence of any of one to four amino acids as a nitrogen source necessary for growth. (2) When a growth-promoting culture medium is inoculated with the species andEscherichia coliin the same count and subjected to anaerobic mixed culturing at 37° C., the final count of lactobacilli is 50% or more of the coliform count. (3) Upon cultivation in an appropriate culture medium, the final pH value is 4.0 or below, and the highest acidity is 1.5% or more. (4) The species is resistant to 5% bile salts. (5) The species produces an antibiotic.

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