Lactobacillus iners for the enhancement of urogenital health

Details Lactobacillus iners for the enhancement of urogenital health Lactobacillus iners for the enhancement of urogenital health

2003-03-28

2010-11-09

Leavitt, Maria (Department: 1633)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Bacteria or actinomycetales

C424S430000, C424S535000, C435S252900

Reexamination Certificate

active

07829079

ABSTRACT:
The present invention provides methods and compositions for administration ofLactobacillus inersalone or together with at least one other probiotic organism such asBifordobacterium, or anotherLactobacillusfor reduction of the risk of urogenital infection and concomitant restoration and/or maintenance of a healthy urogenital flora. A method of treatment of vaginal infections is also contemplated.

REFERENCES:
patent: 6277370 (2001-08-01), Cavaliere Ved. Vesely et al.
patent: 6468526 (2002-10-01), Chrisope
patent: 6479051 (2002-11-01), Bruce et al.
patent: 7220418 (2007-05-01), Hans et al.
patent: WO 93/09793 (1993-05-01), None
patent: WO 00/35465 (2000-06-01), None
patent: WO01/02570 (2001-01-01), None
Nugent et al., J Clin Microbiol. Feb. 1991;29(2):297-301.Reliability of diagnosing bacterial vaginosis is improved by a standardized method of gram stain interpretation.
Gibson et al., Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin.Gastroenterology. Apr. 1995;108(4):975-82.
Mims et al., Medical Microbiology, Third Edition. Mosby Elsenvier Science. pp. 214-215, 246-247, 194-196, 270-271.
Reid et al., Probiotic Lactobacillus dose required to restore and maintain a normal vaginal flora. FEMS Immunol Med Microbiol. Dec. 2001;32(1):37-41.
Sobel JD Bacterial vaginosis.Annu Rev Med. 2000;51:349-56.
Russell-Jones G.J. Oral vaccine deliveryJ. Control Release 65 (2000), pp. 49-54.
Cherpes et al., Association between acquisition of herpes simplex virus type 2 in women and bacterial vaginosis. Clin Infect Dis. Aug. 1, 2003;37(3):319-25. Epub Jul. 15, 2003. Abstract.
Anukam et al.,Lactobacillusvaginal microbiota of women attending a reproductive health care service in Benin city, Nigeria. Sex Transm Dis. Jan. 2006;33(1):59-62. Abstract.
Anukan et al., Augmentation of antimicrobial metronidazole therapy of bacterial vaginosis with oral probioticLactobacillus rhamnosusGR-1 andLactobacillus reuteriRC-14: randomized, double-blind, placebo controlled trialMicrobes and Infection vol. 8, Issue 6, May 2006, pp. 1450-1454.
Ferris et al., Cultivation-Independent Analysis of Changes in Bacterial Vaginosis Flora Following Metronidazole TreatmentJournal of Clinical Microbiology, Mar. 2007, p. 1016-1018, vol. 45, No. 3.
Saunders et al., Effect ofLactobacilluschallenge onGardnerella vaginalisbiofilms. Colloids Surf B Biointerfaces. Apr. 1, 2007;55(2):138-42. Epub Dec. 9, 2006.
Ferris et al., Cultivation-Independent Analysis of Changes in Bacterial Vaginosis Flora Following Metronidazole Treatment. J Clin Microbiol. Mar. 2007; 45(3): 1016-1018.
Columbia Agar, Difco.
Macfarlane et al., Probiotics and prebiotics: can regulating the activities of intestinal bacteria benefit health? BMJ 1999;318:999-1003 (Apr. 10).
Dicks et al., Int J Syst Evol Microbiol. May 2000;50 Pt 3:1253-8.Lactobacillus fornicalissp. nov., isolated from the posterior fornix of the human vagina.
Falsen, E. et al., “Phenotypic and phylogenetic characterization of a novelLactobacillusspecies from human sources: description ofLactobacillus inerssp. Nov.”,International Journal of Systematic Bacteriology49: 217-221 (1999).
Burton, J. P. et al., “Improved Understanding of the Bacterial Vaginal Microbiota of Women before and after Probiotic Instillation”,Applied and Environmental Microbiology69(1): 97-101 (2003).
Dicks, L. M. T., et al., “Lactobacillus fomicalissp. Nov., isolated from the posterior fornix of the human vagina”,International Journal of Systematic and Evolutionary Microbiology50: 1253-1258.
Gancheva, A., et al., “A Polyphasic Approach towards the Identification of Strains Belonging toLactobacillus acidophilusand Related Species”,System. Appl. Microbiol. 22: 573-585 (1999).
Vasquez, A., et al., “VaginalLactobacillusFlora of Healthy Swedish Women”,Journal of Clinical Microbiology, 40(8): 2746-2749 (2002).

Affiliated with

Also associated with

Rating

Lactobacillus iners for the enhancement of urogenital health does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Lactobacillus iners for the enhancement of urogenital health, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Lactobacillus iners for the enhancement of urogenital health will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4152665