Lactobacillus acidophilus nucleic acids and uses thereof

Details Lactobacillus acidophilus nucleic acids and uses thereof Lactobacillus acidophilus nucleic acids and uses thereof

2005-10-27

2008-12-23

Prouty, Rebecca E. (Department: 1652)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

C435S189000, C435S252900, C435S252100, C435S069100, C435S006120, C435S320100, C435S325000, C536S023200, C424S093450

Reexamination Certificate

active

07468182

ABSTRACT:
Lactobacillus acidophilusNCFM nucleic acid molecules, polypeptides, fragments and variants thereof are provided in the current invention. In addition, fusion proteins, antigenic peptides, and antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells comprising the expression vectors. Methods for producing the polypeptides of the invention and methods for their use are further provided.

REFERENCES:
patent: 5837509 (1998-11-01), Israelsen et al.
patent: 6451584 (2002-09-01), Tomita et al.
patent: 6476209 (2002-11-01), Glenn et al.
patent: 6544772 (2003-04-01), Glenn et al.
patent: 6635460 (2003-10-01), Van Hijum et al.
patent: 2002/0061292 (2002-05-01), De Simone
patent: 2002/0159976 (2002-10-01), Glenn et al.
patent: 2003/0138822 (2003-07-01), Glenn et al.
patent: 2004/0009490 (2004-01-01), Glenn et al.
patent: 2004/0208863 (2004-10-01), Versalovic et al.
patent: 2005/0003510 (2005-01-01), Chang et al.
patent: 2005/0112612 (2005-05-01), Klaenhammer et al.
patent: 2005/0123941 (2005-06-01), Klaenhammer et al.
patent: 2005/0250135 (2005-11-01), Klaenhammer et al.
patent: 0 888 118 (1999-01-01), None
patent: WO 98/52586 (1998-11-01), None
patent: WO 02/12506 (2002-02-01), None
patent: WO 02/074798 (2002-09-01), None
patent: WO 03/084989 (2003-10-01), None
patent: WO 2004/020467 (2004-03-01), None
patent: WO 2004/031389 (2004-04-01), None
patent: WO 2004/069178 (2004-08-01), None
patent: WO 2004/096992 (2004-11-01), None
patent: WO 2005/001057 (2005-01-01), None
patent: WO 2005/012491 (2005-02-01), None
patent: WO 2005/081959 (2005-09-01), None
patent: WO 2005/084411 (2005-09-01), None
patent: WO 2005/086794 (2005-09-01), None
Peck et al. (Genbank Accession No. AAV34838).
Abee et al. (1994) “Kinetic studies of the action of lactacin F, a bacteriocin produced byLactobacillus johnsoniithat forms poration complexes in the cytoplasmic membrane”Appl. Environ. Microbiol. 60:1006-10013.
Allison and Klaenhammer (1996) “Functional analysis of the gene encoding immunity to lactacin F,lafl, and its use as aLactobacillus- specific, food-grade genetic marker”Appl. Environ. Microbiol. 62:4450-4460.
Allison and Klaenhammer (1999) “Genetics of bacteriocins produced by lactic acid bacteria and their use in novel industrial applications”in Manual of Industrial Microbiology and Biotechnology. DeMain and Davies (eds.), ASM Press, Washington, D.C., pp. 789-808.
Allison et al. (1994) “Expansion of bacteriocin activity and host range upon complementation of two peptides encoded with the lactacin F operon”J. Bacteriol. 176:2235-2241.
Altermann et al. (2004) “Identification and phenotypic characterization of the cell-division protein CdpA”Gene342:189-197.
Altermann et al. (2005) “Complete genome sequence of the probiotic lactic acid bacteriumLactobacillus acidophilusNCFM”Proc. Natl. Acad. Sci. U.S.A. Early Edition 10.1073/pnas.0409188102, online publication date Jan. 25, 2005.
Azcarate-Peril et al. (2004) “Identification and inactivation of genetic loci involved withLactobacillus acidophilusacid tolerance”Appl. Environ. Microbiol. 70:5315-5322.
Barefoot and Klaenhammer (1983) “Detection and activity of lactacin B, a bacteriocin produced byLactobacillus acidophilus” Appl. Environ. Microbiol. 45:1808-1815.
Barefoot and Klaenhammer (1984) “Purification and characterization of theLactobacillus acidophilusbacteriocin lactacin B”Antimicrob. Agents Chemother. 26:328-334.
Barefoot et al. (1994) “Identification and purification of a protein that induces production of theLactobacillus acidophilusbacteriocin lactacin B”Appl. Environ. Microbiol. 60:3522-3528.
Barrangou et al. (2003) “Functional and comparative genomic analyses of an operon involved in fructooligosaccharide utilization byLactobacillus acidophilus” Proc. Natl. Acad. Sci. U.S.A. 100:8957-8962.
Boels et al. (2001) “Functional analysis of theLactococcus lactis galU andgalE genes and their impact on sugar nucleotide and exopolysaccharide biosynthesis”Appl. Environ. Microbiol. 67:3033-3040.
Bruno-Barcena et al. (2004) “Expression of heterologous manganese superoxide dismutase gene in intestinal lactobacilli provides protection against hydrogen peroxide toxicity”Appl. Environ. Microbiol. 70:4702-4710.
Christensen et al. (1999) “Peptidases and Amino Acid Catabolism in Lactic Acid Bacteria”Antonie van Leeuwenhoek76: 217-246.
Coconnier et al. (1992) “Protein-mediated adhesion ofLactobacillus acidophilusBG2FO4 on human enterocyte and mucus -secreting cell lines in culture”Appl. Environ. Microbiol. 58:2034-2039.
Contreras et al. (1997) “Isolation, purification and amino acid sequence of lactobin A, one of the two bacteriocins produced byLactobacillus amylovorusLMG P-13139”Appl. Environ. Microbiol. 63:13-20.
De Vuyst and Degeest (1998) “Heteropolysaccharides from lactic acid bacteria”FEMS Microbiol. Rev. 23:153-177.
Dodd and Gasson (1994) “Bacteriocins of lactic acid bacteria”in Genetics and Biotechnology of Lactic Acid Bacteria. Gasson and de Vos (eds.), Blackie Academic and Professional, London, pp. 211-251.
Fremaux et al. (1993) “Molecular analysis of the lactacin F operon”Appl. Environ. Microbiol. 59:3906-3915.
GenBank Accession No. AAA19050; Prolinase; Source;Lactobacillus helveticus.
GenBank Accession No. AAA25250; Aminopeptidase C.; Source:Lactobacillus helveticus.
GenBank Accession No. AAB52540; Endopeptidase; Source:Lactobacillus helveticus.
GenBank Accession No. AAB66326; GroEL; Source:Lactobacillus zeae.
GenBank Accession No. AAC29003; cochaperonin GroES; Source:Lactobacillus helveticus.
GenBank Accession No. AAC99363; D-lactate dehydrogenase; Source:Lactobacillus johnsonii.
GenBank Accession No. AAF22492; F1F0-ATPase subunit a; Source:Lactobacillus acidophilus.
GenBank Accession No. AAF22494; F1F0-ATPase subunit b; Source:Lactobacillus acidophilus.
GenBank Accession No. AAF22495; F1F0-ATPase subunit delta; Source:Lactobacillus acidophilus.
GenBank Accession No. AAF22496; F1F0-ATPase subunit alpha; Source:Lactobacillus acidophilus.
GenBank Accession No. AAF22497; F1F0-ATPase subunit gamma; Source:Lactobacillus acidophilus.
GenBank Accession No. AAF22498; F1F0-ATPase subunit beta; Source:Lactobacillus acidophilus.
GenBank Accession No. AAF22499; F1F0-ATPase subunit epsilon; Source:Lactobacillus acidophilus.
GenBank Accession No. AAF75593; GroEL; Source:Lactobacillus johnsonii.
GenBank Accession No. AAK97217; cochaperonin GroES; Source:Lactobacillus acidophilus.
GenBank Accession No. AAK97218; chaperonin GroEL; Source:Lactobacillus acidophilus.
GenBank Accession No. AAK97220; cochaperonin GrpE; Source:Lactobacillus acidophilus.
GenBank Accession No. AAK97221; heat shock protein DnaK; Source:Lactobacillus acidophilus.
GenBank Accession No. AAQ72431; Endopeptidase E2; Source:Lactobacillus helveticus.
GenBank Accession No. AAR25444; Tuf;Lactobacillus johnsonii.
GenBank Accession No. AAT09141; amino acid permease La995; Source:Lactobacillus acidophilus.
GenBank Accession No. AF010281; Lactobacillus zeae GroES; Source:Lactobacillus zeae.
GenBank Accession No. AF031929; Lactobacillus helveticus cochaperonin GroES and chaperonin GroEL genes, complete cds and DNA mismatch repair enzyme (hexA) gene, partial cds; Source:Lactobacillus helveticus.
GenBank Accession No. AF071558; Lactobacillus johnsonii D-lactate dehydrogenase (ldhD) gene, complete cds; Source:Lactobacillus johnsonii.
GenBank Accession No. AF098522; Lactobacillus acidophilus uracil phosphoribosyltransferase; Source:Lactobacillus acidophilus.
GenBank Accession No. AF214488; Lactobacillus johnsonii groESL operon, complete sequence and unknown gene; Source:Lactobacillus johnsonii.
GenBank Accession No. AF300645; Lactobacillus acidophilus groESL operon, complete sequence; Source:Lactobacillus acidophilus.
GenBank Accession No. AF300646; Lactobacillus acid

Affiliated with

Also associated with

Rating

Lactobacillus acidophilus nucleic acids and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Lactobacillus acidophilus nucleic acids and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Lactobacillus acidophilus nucleic acids and uses thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4042739