Lactobacillus acidophilus nucleic acid sequences encoding...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S023700, C435S069100, C435S069700, C435S252300, C435S320100

Reexamination Certificate

active

07608700

ABSTRACT:
Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.

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Allison et al. (1994) “Expansion of bacteriocin activity and host range upon complementation of two peptides encoded with the lactacin F operon”J. Bacteriol. 176:2235-2241.
Altermann et al. (2004) “Identification and phenotypic characterization of the cell-division protein CdpA”Gene342:189-197.
Altermann et al. (2005) “Complete genome sequence of the probiotic lactic acid bacteriumLactobacillus acidophilusNCFM”Proc. Natl. Acad. Sci. U.S.A. Early Edition 10.1073/pnas.0409188102, online publication date Jan. 25, 2005.
Azcarate-Peril et al. (2004) “Identification and inactivation of genetic loci involved withLactobacillus acidophilusacid tolerance”Appl. Environ. Microbiol. 70:5315-5322.
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GenBank Accession No. AAA19050; Prolinase; Source:Lactobacillus helveticus.
GenBank Accession No. AAA25250; Aminopeptidase C.; Source:Lactobacillus helveticus.
GenBank Accession No. AAB52540; Endopeptidase; Source:Lactobacillus helveticus.
GenBank Accession No. AAB66326; GroEL; Source:Lactobacillus zeae.
GenBank Accession No. AAC29003; cochaperonin GroES; Source:Lactobacillus helveticus.
GenBank Accession No. AAC99363; D-lactate dehydrogenase; Source:Lactobacillus johnsonii.
GenBank Accession No. AAF22492; F1F0-ATPase subunit a; Source:Lactobacillus acidophilus.
GenBank Accession No. AAF22493; F1F0-ATPase subunit c; Source:Lactobacillus acidophilus.
GenBank Accession No. AAF22494; F1F0-ATPase subunit b; Source:Lactobacillus acidophilus.
GenBank Accession No. AAF22495; F1F0-ATPase subunit delta; Source:Lactobacillus acidophilus.
GenBank Accession No. AAF22496; F1F0-ATPase subunit alpha; Source:Lactobacillus acidophilus.
GenBank Accession No. AAF22497; F1F0-ATPase subunit gamma; Source:Lactobacillus acidophilus.
GenBank Accession No. AAF22498; F1F0-ATPase subunit beta; Source:Lactobacillus acidophilus.
GenBank Accession No. AAF22499; F1F0-ATPase subunit epsilon; Source:Lactobacillus acidophilus.
GenBank Accession No. AAF75593; GroEL; Source:Lactobacillus johnsonii.
GenBank Accession No. AAK97217; cochaperonin GroES; Source:Lactobacillus acidophilus.
GenBank Accession No. AAK97218; chaperonin GroEL; Source:Lactobacillus acidophilus.
GenBank Accession No. AAK97220; cochaperonin GrpE; Source:Lactobacillus acidophilus.
GenBank Accession No. AAK97221; heat shock protein DnaK; Source:Lactobacillus acidophilus.
GenBank Accession No. AAQ72431; Endopeptidase E2; Source:Lactobacillus helveticus.
GenBank Accession No. AAR25444; Tuf;Lactobacillus johnsonii.
GenBank Accession No. AAT09141; amino acid permease La995; Source:Lactobacillus acidophilus.
GenBank Accession No. AF010281;Lactobacillus zeaeGroES; Source:Lactobacillus zeae.
GenBank Accession No. AF031929;Lactobacillus helveticus cochaperoninGroES and chaperonin GroEL genes, complete cds and DNA mismatch repair enzyme (hexA) gene, partial cds; Source:Lactobacillus helveticus.
GenBank Accession No. AF071558;Lactobacillus johnsoniiD-lactate dehydrogenase (ldhD) gene, complete cds; Source:Lactobacillus johnsonii.
GenBank Accession No. AF098522;Lactobacillus acidophilusuracil phosphoribosyltransferase; Source:Lactobacillus acidophilus.
GenBank Accession No. AF214488;Lactobacillus johnsoniigroESL op

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