Lactate dehydrogenase inhibitors in cosmetic compositions

Details Lactate dehydrogenase inhibitors in cosmetic compositions Lactate dehydrogenase inhibitors in cosmetic compositions

1996-01-05

1997-01-21

Jordan, Kimberly

Drug, bio-affecting and body treating compositions

Live hair or scalp treating compositions

Polymer containing

514557, 514574, 514880, A61K 706, A61K 3119

Patent

active

055957307

ABSTRACT:
Certain combinations of lactate dehydrogenase inhibitors and specific carboxylic acids stimulate keratinocyte proliferation and collagen synthesis in skin.

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Linnane, Anthony W., et al., "Mitochondrial DNA Mutation and the Ageing Process: Bioenergy and Pharmacological Intervention", Mutation Research, vol. 275, (1992) pp. 195-208.
Nishitani, Koji et al., "Lactate Dehydrogenase Isozyme Patterns of Normal Human Fibroblasts and their In Vitro-transformed Counterparts Obtained by Treatment with Co-60 Gamma-Rays, SV40 or 4-Nitroquinoline 1-oxide", Gann, 72, Apr. 1981, pp. 300-304.
Fleischmajer, Raul, M.D., et al., "Lactate Dehydrogenase Isozyme Patterns in Blister Fluids", The Journal of Investigative Dermatology, vol. 50, No. 5 (1968), pp. 405-408.
Godtfredson et al., "1,6-dihydro-NAD as an Humidity Induced lactate dehydrogenase inhibitor in NADH Preparations", Carlsberg. Res. Comm., 43(3), (1978), pp. 171-175.
Sheffield et al., "Synthesis of Some 4 Pyridyl Pyruvic Acids as Potential Inhibitors", J. Chem Soc. Perkin Trans. 1, No. 20, 1972, pp. 2506-2512.
Meany et al., "N-substituted Oxamates as Inhibitors of Lactate Dehydrogenase", S. Afr. J. Sci, vol. 77, No. 12, (1981), pp. 566-568.
Nisselbaum et al., "Comparison of the Actions of Human Brain, Liver and Heart Lactic Dehydrogenase Variants on Nucleotide Analogues", J. Biol. Chem., 220, 9, (1964).
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