Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-10-25
2005-10-25
Kifle, Bruck (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S212040, C514S212070, C514S212080, C540S522000, C540S523000, C540S524000, C540S525000, C540S527000
Reexamination Certificate
active
06958329
ABSTRACT:
This invention relates to novel lactams having the Formula (I):to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, more specifically, inhibit the production of Aβ-peptide, thereby acting to prevent the formation of neurological deposits of amyloid protein. More particularly, the present invention relates to the treatment of neurological disorders related to β-amyloid production such as Alzheimer's disease and Down's Syndrome.
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Bristol-Myers Squibb Pharma Company
Kifle Bruck
Pillsbury & Winthrop LLP
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