Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-03-27
2007-03-27
McKane, Joseph K. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S550000
Reexamination Certificate
active
11135240
ABSTRACT:
The present invention is directed to certain lactam compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including emesis, urinary incontinence, depression, and anxiety.
REFERENCES:
patent: 5387595 (1995-02-01), Mills et al.
patent: 5750549 (1998-05-01), Caldwell et al.
patent: 5877191 (1999-03-01), Caldwell et al.
patent: 2002/0042431 (2002-04-01), Finke et al.
patent: WO 97/14671 (1997-04-01), None
Finke Paul E.
Meurer Laura C.
Mills Sander G.
Merck & Co. , Inc.
Nolan Jason M.
Rose David L.
Thies J. Eric
Yuro Raynard
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