Lactam nucleic acids

Details Lactam nucleic acids Lactam nucleic acids

1998-10-15

2000-07-04

Riley, Jezia

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 6, 514 44, 536 231, 536 253, 536 2531, 536 2533, 536 2534, C07H 1900, C07H 2102, C12Q 168, A01N 4304

Patent

active

06084082&

ABSTRACT:
Novel .beta.-lactam monomers bearing various functional groups are prepared. The novel .beta.-lactam monomers can be joined into oligomeric compounds such as via preferred phosphate linkages including phosphodiester and phosphorothioate linkages. Useful functional groups include nucleobases as well as polar groups, hydrophobic groups, ionic groups, aromatic groups and/or groups that participate in hydrogen bonding. The oligomeric compounds are useful as diagnostic and research reagents.

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