Lactam nucleic acids

Details Lactam nucleic acids Lactam nucleic acids

1996-07-19

1999-02-02

Marschel, Ardin H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

540200, 540354, 540357, 540360, C07H 1900, C07D20500, C07D20508

Patent

active

058666915

ABSTRACT:
Novel .beta.-lactam monomers bearing various functional groups are prepared. The novel .beta.-lactam monomers can be joined into oligomeric compounds such as via preferred phosphate linkages including phosphodiester and phosphorothioate linkages. Useful functional groups include nucleobases as well as polar groups, hydrophobic groups, ionic groups, aromatic groups and/or groups that participate in hydrogen bonding. The oligomeric compounds are useful as diagnostic and research reagents.

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