Lactam metalloprotease inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514278, 514 89, 514 91, 546 23, 546153, 546173, A01N 4342, A01N 5724, C07F 932, C07D21520, C07D21506

Patent

active

060573368

ABSTRACT:
The present application describes novel lactams and derivatives thereof of formula I: ##STR1## or pharmaceutically acceptable salt forms thereof, wherein rings ring B is a 4-8 membered cyclic amide containing from 0-3 additional heteroatoms selected from N, O, and S, which are useful as metalloprotease inhibitors.

REFERENCES:
patent: 5795889 (1998-08-01), Spada et al.

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