Lactam derivatives of mercaptoacylamino acids

Details Lactam derivatives of mercaptoacylamino acids Lactam derivatives of mercaptoacylamino acids

1980-10-31

1982-01-26

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424240, 424246, 424250, 424251, 424274, A61K 3140, C07D40112

Patent

active

043128092

ABSTRACT:
Angiotensin converting enzyme inhibitory action is shown in mammals by compounds having the formula ##STR1## wherein R.sub.1 and R.sub.2 are the same or different, and each is hydrogen, halogen, trifluoromethyl, or aminosulfonyl;

REFERENCES:
patent: 4105776 (1978-08-01), Ondetti et al.
patent: 4154935 (1979-05-01), Ondetti et al.
patent: 4168267 (1979-09-01), Petrillo
Helv. Chim. Acta, 42, 1085 (1959).

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