Lactam-containing compounds and derivatives thereof as...

Details Lactam-containing compounds and derivatives thereof as... Lactam-containing compounds and derivatives thereof as...

2011-06-14

2011-06-14

Kifle, Bruck (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S194000

Reexamination Certificate

active

07960411

ABSTRACT:
The present application describes lactam-containing compounds and derivatives thereof of Formula I:in-line-formulae description="In-line Formulae" end="lead"?P4—P-M-M4  Iin-line-formulae description="In-line Formulae" end="tail"?or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.

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