Lactam compounds and pharmaceutical use thereof

Details Lactam compounds and pharmaceutical use thereof Lactam compounds and pharmaceutical use thereof

2006-12-26

2006-12-26

Kifle, Bruck (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C540S557000

Reexamination Certificate

active

07153850

ABSTRACT:
An agent for increasing the sugar-transporting capacity and an agent for preventing and/or treating diabetes, diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic macroangiopathy, impaired glucose tolerance or adiposis, which contains a lactam compound or a pharmaceutically acceptable salt thereof as the active ingredient.

REFERENCES:
patent: 11-171776 (1999-06-01), None
Sorokina, et al. “Synthesis and Pharmacologial Study of Derivatives of Pyrrolo[3,4-b]benzo[1,5]Diazepine”, Pharmaceutical Chemistry Journal, (1991), vol. 25, No. 11, pp. 768-770.
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Matsuo, et al., “Syntheses of the Novel Furo[3,4-b][1,5]benzodiazepinone and Pyrrolo[3,4-b][1,5]benzodiazepinone Systems”, Chem. Pharm. Bull., vol. 32, No. 9, pp. 3724-3729.
Augustin, et al., “A Simple Synthesis of Some New 2-Aryl-Substituted 2,5-Dihydro-1-H-1,5-benzodiazepine- and 2,5-Dihydro-1,5-benzothiazepin-3,4-dicarboxylic N-Arylimides”, Communications (1987), pp. 937-938.
Matsuo, et al. “10-Aryl-3,3-dimethyl-2,3,4, 10-tetrahydro-1H-pyrrolo[3,4-c] [,5]benzothiazepin-1-one”, Journal of the Pharmaceutical Society of Japan, (1984), vol. 104, No. 9, pp. 1004-1008.
Schmidt, et al., “Ring Construction Using 3-(Arylmethylene)-2,4(3H,5H)-furandione: Synthesis of Pyrazolones and Furo[3,4-c][1,5]benzothiazepinones”, (1983), vol. 48, No. 23, pp. 4367-4370.
Keizo Matsuo et al, “Synthesis and Reaction of 10-aryl-3,4,9, 10-tetrahydro-1H-thieno-[4,3-b][1,5]benzodiazepin-1-ones”,Chemistry Express, 1991, vol. 6, No. 7, pp. 495-498.
I. K. Sorokina et al, “Synthesis and Pharmacological Study of Pyrrolo[3,4-b]benzo[1,5]diazepine Derivatives,”Khimiko-Farmatsevticheskli Zhumal, 1991, vol. 25, No. 11, pp. 16-18 (with attached English translation).

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