Labelling colors for detecting cocaine or methamphetamine, metho

Details Labelling colors for detecting cocaine or methamphetamine, metho Labelling colors for detecting cocaine or methamphetamine, metho

1994-10-07

1996-11-05

Ceperley, Mary E.

Chemistry: analytical and immunological testing

Involving immune complex formed in liquid phase

Signal modification or steric inhibition

436546, 436816, 546126, 548490, 548491, G01N 33542, G01N 33533, C07D40106, C07D20914

Patent

active

055717276

ABSTRACT:
A labelling color for detecting cocaine of Formula (I) ##STR1## wherein X represents a halogen, and a method of detecting methamphetamine, including the steps of adding a labelling color of Formula (II) ##STR2## wherein X represents an anion to a first solution of methamphetamine antibody to form a labelling color-methamphetamine antibody complex, measuring the fluorescence of the first solution, adding a sample containing an unknown amount of methamphetamine to the first solution to form a second solution, measuring the fluorescence of the second solution, and correlating any change in the fluorescence between the first and second solutions to the concentration of methamphetamine in the sample.

REFERENCES:
patent: 3833863 (1974-09-01), Webster et al.
patent: 3904613 (1975-09-01), Schmitt
patent: 4344879 (1982-10-01), Mohr et al.
U. Mushkalko et al., Ukr. Khim. Zh. (Russ. Ed), vol. 52, No. 5, pp. 509-513 (1986).
J. March, Advanced Organic Chemistry, Reactions, Mechanisms, and Structure, pp. 326 and 327, McGraw-Hill, Inc., NY (1977).
R. Morrison et al., Organic Chemistry, Second Edition, pp. 732 and 733, Allyn and Bacon, Inc., Boston (1967).

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