Labelled nucleotides

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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Details

C536S024300, C536S026600, C435S006120, C435S091100, C435S091200

Reexamination Certificate

active

07414116

ABSTRACT:
The invention provides a nucleotide or nucleoside having a base attached to a detectable label via a cleavable linker, characterised in that the cleavable linker contains a moiety selected from the group comprising: Formula (I) wherein X is selected from the group comprising O, S, NH and NQ wherein Q is a C1-10substituted or unsubstituted alkyl group, Y is selected from the group comprising O, S, NH and N(allyl), T is hydrogen or a C1-10substituted or unsubstituted alkyl group and * indicates where the moiety is connected to the remainder of the nucleotide or nucleoside).

REFERENCES:
patent: 4711955 (1987-12-01), Ward et al.
patent: 4772691 (1988-09-01), Herman
patent: 5302509 (1994-04-01), Cheeseman
patent: 5436143 (1995-07-01), Hyman
patent: 5516664 (1996-05-01), Hyman
patent: 5547839 (1996-08-01), Dower et al.
patent: 5602000 (1997-02-01), Hyman
patent: 5763594 (1998-06-01), Hiatt et al.
patent: 5872244 (1999-02-01), Hiatt et al.
patent: 6008379 (1999-12-01), Benson et al.
patent: 6087095 (2000-07-01), Rosenthal et al.
patent: 6214987 (2001-04-01), Hiatt et al.
patent: 6255475 (2001-07-01), Kwiatkowski
patent: WO 91/06678 (1991-05-01), None
patent: WO 92/10587 (1992-06-01), None
patent: WO 94/14972 (1994-07-01), None
patent: WO 96/07669 (1996-03-01), None
patent: WO 99/05315 (1999-02-01), None
patent: WO 99/57321 (1999-11-01), None
patent: WO 00/02895 (2000-01-01), None
patent: WO 0015844 (2000-03-01), None
patent: WO 00/53812 (2000-09-01), None
patent: WO 01/23610 (2001-04-01), None
patent: WO 01/57249 (2001-08-01), None
patent: WO 02/29003 (2002-04-01), None
J. Brunckova et al., Tetrahedron Letters, (1994), vol. 35, pp. 6619-6622.
S. Nishino et al., Heteroatom Chemistry, (1991), vol. 2, pp. 187-196.
M. Krecmerová et al., Collect. Czech. Chem. Commun., (1990), vol. 55, pp. 2521-2536.
P. J. L. M. Quaedflieg et al., Tetrahedron Letters, (1992), vol. 33, No. 21, pp. 3081-3084.
J. I. Yamashita et al., Chem Pharm. Bull., (1987), vol. 35, pp. 2373-2381.
S.G. Zavgorodny et al., Nucleosides, Nucleotides & Nucleic Acids, (2000), 19(10-12), 1977-1991.
Kraevskii et al., Substrate Inhibitors of DNA Biosynthesis, Translated from Molekulyamaya Biologiya [Mol. Bio. (Mosk.)] 21:33-38 (1987).
Henner et al., Enzyme Action at 3' Termini of Ionizing Radiation-induced DNA Strand Breaks, The Journal of Biological Chemistry, 258:15198-15205 (1983).

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