Labelled nucleotides

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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Details

C536S026600, C435S006120, C435S091100

Reexamination Certificate

active

07427673

ABSTRACT:
Nucleosides and nucleotides are disclosed that are linked to detectable labels via a cleavable linker group.

REFERENCES:
patent: 4711955 (1987-12-01), Ward et al.
patent: 4772691 (1988-09-01), Herman
patent: 4824775 (1989-04-01), Dattagupta et al.
patent: 4863849 (1989-09-01), Melamede
patent: 5118605 (1992-06-01), Urdea
patent: 5174962 (1992-12-01), Brennan
patent: 5175269 (1992-12-01), Stavrianopoulos
patent: 5302509 (1994-04-01), Cheeseman
patent: 5328824 (1994-07-01), Ward et al.
patent: 5436143 (1995-07-01), Hyman
patent: 5449767 (1995-09-01), Ward et al.
patent: 5476928 (1995-12-01), Ward et al.
patent: 5516664 (1996-05-01), Hyman
patent: 5534424 (1996-07-01), Uhlen et al.
patent: 5547839 (1996-08-01), Dower et al.
patent: 5547859 (1996-08-01), Goodman et al.
patent: 5602000 (1997-02-01), Hyman
patent: 5763594 (1998-06-01), Hiatt et al.
patent: 5770367 (1998-06-01), Southern et al.
patent: 5798210 (1998-08-01), Canard et al.
patent: 5808045 (1998-09-01), Hiatt et al.
patent: 5821356 (1998-10-01), Khan et al.
patent: 5849542 (1998-12-01), Reeve et al.
patent: 5872244 (1999-02-01), Hiatt et al.
patent: 5885775 (1999-03-01), Haff et al.
patent: 6001566 (1999-12-01), Canard et al.
patent: 6008379 (1999-12-01), Benson et al.
patent: 6046005 (2000-04-01), Ju et al.
patent: 6074823 (2000-06-01), Koster
patent: 6087095 (2000-07-01), Rosenthal et al.
patent: 6136543 (2000-10-01), Anazawa et al.
patent: 6214987 (2001-04-01), Hiatt et al.
patent: 6218118 (2001-04-01), Sampson et al.
patent: 6218530 (2001-04-01), Rothschild et al.
patent: 6232465 (2001-05-01), Hiatt et al.
patent: 6242193 (2001-06-01), Anazawa et al.
patent: 6255475 (2001-07-01), Kwiatkowski
patent: 6287821 (2001-09-01), Shi et al.
patent: 6309836 (2001-10-01), Kwiatkowski et al.
patent: 6312893 (2001-11-01), Van Ness et al.
patent: 6524829 (2003-02-01), Seeger
patent: 6613508 (2003-09-01), Van Ness et al.
patent: 6639088 (2003-10-01), Kwiatkowski
patent: 6664079 (2003-12-01), Ju et al.
patent: 6780591 (2004-08-01), Williams et al.
patent: 6787308 (2004-09-01), Balasubramanian et al.
patent: 6911345 (2005-06-01), Quake et al.
patent: 6982146 (2006-01-01), Schneider et al.
patent: 7037687 (2006-05-01), Williams et al.
patent: 7056666 (2006-06-01), Dower et al.
patent: 7057026 (2006-06-01), Barnes et al.
patent: 7057031 (2006-06-01), Olejnik et al.
patent: 7074597 (2006-07-01), Ju
patent: 7078499 (2006-07-01), Odedra et al.
patent: 7105300 (2006-09-01), Parce et al.
patent: 2003/0008285 (2003-01-01), Fischer
patent: 2003/0104437 (2003-06-01), Barnes et al.
patent: 2003/0186256 (2003-10-01), Fischer
patent: 41 41 178 (1993-06-01), None
patent: 0 808 320 (1997-11-01), None
patent: 0 992 511 (2000-04-01), None
patent: 1 182 267 (2002-02-01), None
patent: 1 291 354 (2003-03-01), None
patent: 1 337 541 (2007-03-01), None
patent: 1218 391 (2007-04-01), None
patent: 1 790 736 (2007-05-01), None
patent: WO 89/09282 (1989-10-01), None
patent: WO 90/13666 (1990-11-01), None
patent: WO 91/06678 (1991-05-01), None
patent: WO 92/10587 (1992-06-01), None
patent: WO 93/05183 (1993-03-01), None
patent: WO 93/21340 (1993-10-01), None
patent: WO 94/14972 (1994-07-01), None
patent: WO 96/07669 (1996-03-01), None
patent: WO 96/23807 (1996-08-01), None
patent: WO 96/27025 (1996-09-01), None
patent: WO 99/05315 (1999-02-01), None
patent: WO 99/57321 (1999-11-01), None
patent: WO 00/02895 (2000-01-01), None
patent: WO 00/06770 (2000-02-01), None
patent: WO 0015844 (2000-03-01), None
patent: WO 00/18956 (2000-04-01), None
patent: WO 00/21974 (2000-04-01), None
patent: WO 00/50642 (2000-08-01), None
patent: WO 00/53805 (2000-09-01), None
patent: WO 00/53812 (2000-09-01), None
patent: WO 00/70073 (2000-11-01), None
patent: WO 01/16375 (2001-03-01), None
patent: WO 01/23610 (2001-04-01), None
patent: WO 01/25247 (2001-04-01), None
patent: WO 01/32930 (2001-05-01), None
patent: WO 01/57248 (2001-08-01), None
patent: WO 01/57249 (2001-08-01), None
patent: WO 01/92284 (2001-12-01), None
patent: WO 02/02813 (2002-01-01), None
patent: WO 02/22883 (2002-03-01), None
patent: WO 02/29003 (2002-04-01), None
patent: WO 02/072892 (2002-09-01), None
patent: WO 02/079519 (2002-10-01), None
patent: WO 02/088381 (2002-11-01), None
patent: WO 02/088382 (2002-11-01), None
patent: WO 03/002767 (2003-01-01), None
patent: WO 03/020968 (2003-03-01), None
patent: WO 03/048178 (2003-06-01), None
patent: WO 03/048387 (2003-06-01), None
patent: WO 03/048387 (2003-10-01), None
patent: WO 03/085135 (2003-10-01), None
patent: WO 2004/007773 (2004-01-01), None
patent: WO 2004/018493 (2004-03-01), None
patent: WO 2004/018497 (2004-03-01), None
patent: WO 2004/018497 (2004-06-01), None
patent: WO 2005/084367 (2005-09-01), None
S.G. Zavgorodny et al., Nucleosides, Nucleotides and Nucleic Acids, 19(10-12), 1977-1991 (2000).
Kraevskii et al., Substrate Inhibitors of DNA Biosynthesis, Translated from Molekulyarnaya Biologiya [Mol. Bio. (Mosk.)] 21:33-38 (1987).
Henner et al., Enzyme Action at 3′ Termini of Ionizing Radiation-induced DNA Strand Breaks, The Journal of Biological Chemistry, 258:15198-15205 (1983).
U.S. Appl. No. 10/525,399, filed Feb. 23, 2005, Milton et al.
U.S. Appl. No. 11/301,578, filed Dec. 23, 2005, Barnes et al.
U.S. Appl. No. 90/008,149, filed Aug. 4, 2006, Gitten.
U.S. Appl. No. 90/008,152, filed Aug. 3, 2006, Gitten.
Canard et al., DNA polymerase fluorescent substrates with reversible 3′-tags, Gene, 148:1-6 (1994).
Metzker et al., Termination of DNA synthesis by novel 3′-modified-deoxyribonucleoside 5′-triphosphates, Nucleic Acids Research, 22:4259-4267 (1994).
Hovinen et al., Synthesis of 3′—O—(ω-Aminoalkoxymethyl) thymidine 5′—Triphosphates, Terminators of DNA Synthesis that Enable 3′-Labelling, J. Chem. Soc. Perkin Trans, 2:211-217 (1994).
Ikeda et al., A Non-radioactive DNA Sequencing Method Using Biotinylated Dideoxynucleoside Triphosphates and ΔTth DNA Polymerase, 2:225-227 (1995).
Welch et al., Syntheses of Nucleosides Designed for Combinatorial DNA Sequencing, Chemistry, European Journal, 5:951-960 (1999).
Canard et al., Catalytic editing properties of DNA polymerases, Proc. Natl. Acad. Sci., 92:10859-10863 (1995).
Olejnik et al., Photocleavable biotin derivatives: A versatile approach for the isolation of biomolecules, Proc. Natl. Acad. Sci., 92:7590-7594 (1995).
Wada et al., 2-(Azidomethyl)benzoyl as a new protecting group in nucleosides, Tetrahedron Letters, 42:1069-1072 (2001).
Li et al., A photocleavable fluorescent nucleotide for DNA sequencing and analysis, Proc. Natl. Acad. Sci., 100:414-419 (2003).
Sarfati et al., Synthesis of fluorescent derivatives of 3′-O-(6-aminohexanoyl)-pyrimidine nucleosides 5′-triphosphates that act as DNA polymerase substrates reversibly tagged at C-3′, JCS Perkin Trans, 1163-1171 (1995).
Burgess et al., An Approach to Photolabile, Fluorescent Protecting Groups, J. Org. Chem., 62:5165-5168 (1997).
Rasolonjatovo et al., 6-N- (N-Methylanthranylamido)-4-Oxo-Hexanoic Acid : A New Fluorescent Protecting Group Applicable to a New DNA Sequencing Method, Nucleosides & Nucleotides, 17:2021-2025 (1998).
Marquez et al., Selective Fluorescence Quenching of 2,3-Diazabicyclo[2.2.2]oct-2-ene by Nucleotides, Organic Letters, 5:3911-3914 (2003).
Nazarenko et al., Effect of primary and secondary structure of oligodeoxyribonucleotides on the fluorescent properties of conjugated dyes, Nucleic Acids Research, 30:2089-2095 (2002).
Kvam et al., Characterization of singlet oxygen-induced guanine residue damage after photochemical treatment of free nucleosides and DNA, Biochimica et Biophysica Acta., 1217:9-15 (1994).
Crespo-Hernandez et al., Part 1. Photochemical and Photophysical Studies of Guanine Derivatives: Intermediates Contributing to its Photodestruction Mechanism in Aqueous Solution and the Participation of the Electron Adduct, Photochemistry and Photobiology, 71(5):534-543 (2000).
Buschmann et al., Spectroscopic Study and Evaluation of Red-Absorbing Flourescent Dyes, Bioconjugate Chem., 14:195-204 (2003).
Torimura et al

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