Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Attached to lymphokine – cytokine – or other secreted growth...
Patent
1992-10-05
1995-05-09
Stoll, Robert L.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Attached to lymphokine, cytokine, or other secreted growth...
530402, 530408, 530409, A61K 4902
Patent
active
054137780
ABSTRACT:
A method of imaging a target site in an animal's body in which a labelled CC chemokine or Monocyte Attractant Protein (MCP) material is introduced into the animal's body and allowed to accumulate at a target site which includes MCP receptor molecules. The accumulated, labelled MCP material is then detected so as to image the target site of the body.
REFERENCES:
patent: 4276280 (1981-06-01), Akerkar et al.
patent: 4520112 (1985-05-01), Snyder et al.
patent: 4656280 (1987-04-01), Garlick
patent: 4659839 (1987-04-01), Nicolotti et al.
patent: 4732974 (1988-03-01), Nicolotti et al.
patent: 4837003 (1989-06-01), Nicolotti
patent: 4926869 (1990-05-01), Rubin et al.
patent: 4965392 (1990-10-01), Fritzberg et al.
patent: 4986979 (1991-01-01), Morgan, Jr. et al.
patent: 5037630 (1991-08-01), Fritzberg et al.
patent: 5079228 (1992-01-01), Cohen et al.
patent: 5179078 (1993-01-01), Rollins et al.
patent: 5196510 (1993-03-01), Rodwell et al.
patent: 5198424 (1993-03-01), McEver
patent: 5241049 (1993-08-01), Goodman et al.
Chem. Abs. 113(13):113534x (1990) Yoshimura et al., J. Immunol., vol. 145, No. 1 pp. 292-297.
R. Ross, "The Pathogenesis of Atherosclerosis", N. Eng. J. Med. 314, pp. 488-500 (1986).
T. J. Standford, B&BRC, vol. 171, pp. 531-536 (1990).
V. M. Elner, Am J. Pathol, vol. 136, pp. 745-750 (1990).
A. J. Thronton, J. Immunol, vol. 144, pp. 2609-2613 (1990).
A. K. Samanta, J. Exp. Med., vol. 169, pp. 1185-1189 (1989).
C. A. Herbert et al., J. Immunol. vol. 145, pp. 3033-3040 (1990).
P. M. Grob, JBC, vol. 265, pp. 8311-8316 (1990).
J. Besemer, et al., JBC, vol. 264, pp. 17409-17415 (1989).
Robinson, et al., "Complete Amino Acid . . . Immune Reactions", Proc. Natl. Acad. Sci. USA, vol. 86, pp. 1850-1854, Mar. 1989.
Nelken, et al., "Monocyte Chemoattractant . . . Atheromatous Plaques", J. Clin. Invest., vol. 88, pp. 1121-1127, Oct. 1991.
Jiang, et al., "Monocyte Chemoattractant . . . In Human Monocytes", The Journal of Immunology, vol. 148, No. 8, pp. 2423-2428, Apr. 1992.
J. Wang, et al., "Human Recombinant Macrophase Inflammatory Protein-1.alpha. and -.beta. and Monocyte Chemotactic and Activating Factor . . . " J. Immunol., vol. 150, No. 7, pp. 3022-3029, (Apr. 1, 1993).
K. Neote, et al., "Identification of a Promiscuous Inflammatory Peptide Receptor . . . ", J. Bio. Chem., vol. 268, No. 17, pp. 12247-12239 (Jun. 15, 1993).
Kunkel Steven L.
Lyle Leon R.
Strieter Robert M.
Chapman Lara E.
Mallinckrodt Medical Inc.
Stoll Robert L.
The Regents of the University of Michigan
LandOfFree
Labelled monocyte chemoattractant protein material and medical u does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Labelled monocyte chemoattractant protein material and medical u, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Labelled monocyte chemoattractant protein material and medical u will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1703884