Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...
Patent
1982-06-30
1985-05-07
Nucker, Christine M.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
2605024P, 424 9, A61K 4300, A61K 4900, C07F 902
Patent
active
045157669
ABSTRACT:
The composition and methodology associated with the formulation of a halogenated phosphonic acid labeled in the ring moiety are disclosed having the formula: ##STR1## wherein R.sub.1 is aryl and is labeled with a halogen and R.sub.2 is hydrogen, alkyl, alkenyl, amino, benzyl, hydroxyl--CH.sub.2 PO.sub.3 H --CH.sub.2 CH.sub.2 PO.sub.3 H.sub.2 and is labeled with halogen. The compositions are especially useful for scanning investigations of in vivo deposits of calcium.
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Castronovo Frank P.
Potsaid Majic S.
Strauss Harry W.
Cook Paul J.
Guthrie Marvin C.
Nucker Christine M.
The Massachusetts General Hospital
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