Labeled hydantoin conjugate and its use in analytical element an

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435188, 435805, 436501, 436523, 436528, 436170, 436816, 422 56, 548308, G01N 3353, G01N 148, G01N 33566, G01N 33543, G01N 33544, G01N 2177, C12N 996, C07D23530

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047525681

ABSTRACT:
A heterogeneous, competitive binding immunoassay for either phenytoin or phenobarbital is conducted with a labeled conjugate comprising a derivative of hydantoin and a label. The hydantoin derivative is 5-ethyl,5-phenyl hydantoin and it is linked to the label (e.g. an enzyme) with a linkage derived from an aliphatic monocarboxylic acid. The immunoassay can be carried out either in solution or with a dry analytical element.

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