Labeled complex

Details Labeled complex Labeled complex

1992-06-18

1996-04-30

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 6, 435 71, 585 26, C12Q 168

Patent

active

055124461

ABSTRACT:
To provide a reagent with excellent stability under storage, which can detect a subject compound to be measured with higher specificity and sensitibity.
Complexes of a compound represented by the general formula (I): ##STR1## (wherein R.sub.1 through R.sub.7 independently represent hydrogen atom, halogen atom, alkyl group, aryl group, aralkyl group, sulfonate group, amino group, styryl group, nitro group, hydroxyl group, carboxyl group, cyano group, or aryl azo group; R.sub.1 through R.sub.7 may or may not be bonded to each other to form a substituted or an unsubstituted condensed ring; R represents a divalent organic residue; and X.sub.1.sup..crclbar. represents an anion) and the like with immunoglobulin and the like are formed.

REFERENCES:
patent: 3770383 (1973-11-01), Price
patent: 3789116 (1974-01-01), Kay
patent: 4738908 (1988-04-01), Oguchi et al.
patent: 5112960 (1992-05-01), Bronstein et al.
Smith et al., Nature, vol. 321, (1986) pp. 674-679.
Derwent Abstract Accession No. 91-068399/10, Japanese patent No. JP 3015746, (Jan. 24, 1991).
K. Sauda et al., "Determination of Protein in Human Serum by High-Performance Liquid Chromatography with Semiconductor Laser Fluorometric Detection," Analytical Chemistry, vol. 58, No. 13, Nov. 1986, pp. 2649-2653.

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