Labeled 5,5-diphenylhydantoin derivatives for radioimmunoassay

Details Labeled 5,5-diphenylhydantoin derivatives for radioimmunoassay Labeled 5,5-diphenylhydantoin derivatives for radioimmunoassay

1976-04-05

1978-05-30

Phillips, Delbert R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

2601125R, 548309, 424 15, C07D23372

Patent

active

040924793

ABSTRACT:
Derivatives of 5,5-diphenylhydantoin having the following structural formula: ##STR1## where R is 2-acetyl, 3-propionyl, 4-butyryl or 5-valeryl and X is an unlabeled or radioiodinated amino radical; e.g., (tyrosine, histidine, tyrosinol, histamine). A preferred compound is radioiodinated 5,5-diphenyl-3-(5-valeryl-N-tyrosine) hydantoin. The iodine isotope may be iodine-125 or iodine-131.

REFERENCES:
cook, et al. in Research Communication in (1973), Chemical Pathology and Pharmacology, 5, pp. 767-774.

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