L-threonine importer from Corynebacterium and a...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C435S487000, C435S106000

Reexamination Certificate

active

07863435

ABSTRACT:
The present invention relates to a preparation method of an L-threonine producing strain by utilizing a novel L-threonine importer identified fromCorynebacterium glutamicum. The method can be advantageously used for the production of L-threonine by increasing the fermentation concentration of Lthreonine and the yield per unit thereof.

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patent: 2002/0197605 (2002-12-01), Nakagawa et al.
patent: 2008/0026432 (2008-01-01), Park et al.
Palmieri et al. Threonine diffusion and threonine transport inCorynebactrium glutamicumand their role in threonine production. Arch. Microbiol. 165:48-54, 1996 (the entire article).
Okamoto et al. Hyperproduction of L-threonine by anEscherichia colimutant with impaired L-threonine uptake. Biosci. Biotech. Biochem. 61:1877-1882, 1997.
S. Nakagawa et al., Genbank Accession #BAC00421 Jun. 5, 2002.
J. Kalinowski et al., Genbank Accession #CAF18967, Jan. 22, 2004.
M. Ikeda et al., Appl. Microbiol. Biotechnol., vol. 62, May 2003, pp. 99-109.
J. Kalinowski et al., J. Biotechnol., vol. 104, Sep. 2003, pp. 5-25.
P. Simic et al., J. Bacteriol., vol. 183, No. 18, Sep. 2001, pp. 5317-5324.
L. Palmieri et al., Arch. Microbiol., vol. 165, 1996, pp. 48-54.

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