L-ribose isomerase, its preparation and uses

Details L-ribose isomerase, its preparation and uses L-ribose isomerase, its preparation and uses

1997-05-14

1998-12-08

Prats, Francisco

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Isomerase

435105, C12N 990, C12P 1902

Patent

active

058468048

ABSTRACT:
An L-ribose isomerase which isomerizes aldoses such as L-ribose, D-lyxose, D-talose, D-mannose, L-allose and L-gulose into their corresponding ketoses such as L-ribulose, D-xylulose, D-tagatose, D-fructose, L-psicose and L-sorbose. The enzymatic reaction is a reversible equilibrium reaction. The L-ribose isomerase can be obtained from microorganisms of the genus Acinetobacter.

REFERENCES:
Shimonishi et al, J. Ferment. Bioengineer. 81(6):493-497 (1996).
Holt et al., Bergey's Manual of Determinative Bacteriology, Ninth Edition, pp. 73, 103, 129, 1994.
Institute For Fermentation, Osaka (IFO), "List of Cultures", Microorganisms, Ninth Edition, pp. V-VI, 95, 136, 1992.
K. Izumori et al.,: "Purification, crystallization, a.sub.nd properties of D-ribose isomerase from Mycobacterium-smegmatis", The Journal of Biological Chemistry, vol. 250, No. 20, 1975, pp. 8085-8087.
K. Izumori et al.,: "Induction of D-ribose isomerase by L-ribose in Mycobacterium s.sub.m egmatis", AGRI.sub.c ultural and Biological Chemistry, vol. 44, No. 1, 1980, pp. 223-225.
D.E. Trimur and R.P. Mortlock: "Isolation and characterization of Escherichia coli mutants able to utilize the novel pentose L-ribose", Journal of Bacteriology, vol. 137, No. 8, 1991, pp. 2459-2464.

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