L-glutamic acid derivatives

Details L-glutamic acid derivatives L-glutamic acid derivatives

1989-08-29

1990-04-24

Ford, John M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544320, C07D23948, C07D23949, A61K 31505

Patent

active

049201255

ABSTRACT:
Pyrimidin-5-yl derivatives of L-glutamic acid are anti-neoplastic agents. A typical embodiment is N-(4-[5-(2,6-diamino-4-hydroxypyrimidin-5-yl)-butyl]-thien-2-ylcarboxy)-L- glutamic acid.

REFERENCES:
patent: 4339453 (1982-07-01), Grier et al.

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