L-glutamate-gated chloride channel proteins from...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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C435S320100, C435S325000, C435S254200

Reexamination Certificate

active

07541432

ABSTRACT:
The present invention relates in part to isolated nucleic acid molecules (polynucleotides) which encodeRhipicephalus sanguineusglutamate gated chloride channels. The present invention also relates to recombinant vectors and recombinant hosts which contain a DNA fragment encodingR. sanguineusglutamate gated chloride channels, substantially purified forms of associatedR. sanguineusglutamate gated chloride channels and recombinant membrane fractions comprising these proteins, associated mutant proteins, and methods associated with identifying compounds which modulate associatedRhipicephalus sanguineusglutamate gated chloride channels, which will be useful as insecticides.

REFERENCES:
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patent: 6358701 (2002-03-01), Warmke et al.
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patent: WO-01/30849 (2001-05-01), None
patent: WO-01/74899 (2001-10-01), None
patent: WO-01/96396 (2001-12-01), None
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Cully, et al., “Identification of a Drosophila melanogaster Glutamate-gated Chloride Channel Sensitive to the Antiparasitic . . .” J. Biol Chem 271: 20187-20191 (1996).
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