L-DOPA ethyl ester to treat Parkinson's disease

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

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A61K 3124

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active

056079699

ABSTRACT:
Patients suffering from Parkinson's disease are treated by administering a composition which contains an active ingredient and a pharmaceutically acceptable carrier. The active ingredient comprises L-DOPA ethyl ester in an amount which is at least 97% by weight of the active ingredient and L-DOPA in an amount which is less than 1% by weight of the active ingredient.

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D.R. Cooper et al., "L-Dopa esters as potential prodrugs; behavioural actty in experimental models of Parkinson's disease"; J. Pharm. Pharmacol.; vol. 39: No.8; pp. 627-635.
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Yoshimasa Tomiuchi, et al. Bull. Chem. Soc. Jpn. (Oct. 1992) 65:2599-2603.

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