L-arabinose fermenting yeast

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Fungi

Reexamination Certificate

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C536S023100, C536S023700, C435S320100

Reexamination Certificate

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07846712

ABSTRACT:
An L-arabinose utilizing yeast strain is provided for the production of ethanol by introducing and expressing bacterial araA, araB and araD genes. L-arabinose transporters are also introduced into the yeast to enhance the uptake of arabinose. The yeast carries additional genomic mutations enabling it to consume L-arabinose, even as the only carbon source, and to produce ethanol. Methods of producing ethanol include utilizing these modified yeast strains.

REFERENCES:
patent: 5272071 (1993-12-01), Chappel
patent: 5965408 (1999-10-01), Short
patent: 2003/0186402 (2003-10-01), Londesborough et al.
patent: 2005/0142648 (2005-06-01), Boles et al.
patent: 2005/0260705 (2005-11-01), Better
Saha, “Production of L-arabitol for L-Arabinose by Candida Entomaea andPichia guilliermondii”, Applied Microbiology and Biotechnology, Apr. 1996, vol. 45, No. 3, p. 299-306.
Billard, “Glucose Uptake inKluyveromyces lactis: Role of the HGT1 Gene in Glucose Transport”, J. Bacteriology, Oct. 1996, vol. 178, No. 20, p. 5860-5866.
International Search Report and Written Opinion of the International Searching Authority dated Dec. 11, 2007, for International Application No. PCT/US07/64418.
Becker, “A ModifiedSaccharomyces cerevisiaeStrain that Consumes L-Arabinose and Produces Ethanol”, Applied and Environmental Microbiology, Jul. 2003, vol. 69, No. 7, pp. 4144-4150.
Richard, “The Missing Link in the Fungal L-Arabinose Catabolic Pathway, Identification of the L-Xyulose Reductase Gene”, Biochemistry, 2002, vol. 41, pp. 6432-6437.
Ostergaard, “Metabolic Engineering ofSaccharomyces cerevisiae”, Microbiology and Molecular Biology Reviews, Mar. 2000, vol. 64, No. 1, pp. 34-50.
International Search Report and Written Opinion of the International Searching Authority dated Dec. 11, 2007, for International Application No. PCT/US07/64330.
Alves-Araujo, “Cloning and Characterization of the MAL11 Gene Encoding fromTorulaspora delbrueckii”, FEMS Yeast Research, 2004, 467-476.
Arnold, “When Blind is Better: Protein Design by Evolution”, Nature Biotechnology, Jul. 1998, 617-618, vol. 16.
Day, “Characterization of the Putative Maltose Transporters Encoded by YDL247w and YJRI60c”, Yeast, 2002, 1015-1027.
Shiraishi, “Effect of Surface Modification Using Various Acids on Electrodeposition of Lithium”, Journal of Applied Electrochemistry, 1995, 584-591.
Pina, “Ffz1, A New Transporter Specific for Fructose fromZygosaccharomyces bailii”, Microbiology, 2004, 2429-2433.
Genomewalker, “Universal Kit, User Manual” Clontech Laboratories, Inc., 2007, 1-30.
Barnett, “The Utilization of Sugars by Yeasts”, School of Biological Sciences, 1976, 125-234.
Bowie, “Deciphering the Message in Protein Sequences: Tolerance to Amino Acid Substitutions”, Science, 1990, 1306-1310, vol. 247.
Cosman, “ULBPs, Novel MHC Class . . . Through the NKG2D Receptor”, Immunity, 2001, 123-133, vol. 14.
Crameri, “DNA shuffling of a Family of Genes from Diverse Species Accelerates Directed Evolution”, Nature, 1998, 288-291, vol. 391.
Deanda, “Development of an Arabinose-FermentingZymomonas mobilisStrain by Metabolic Pathway Engineering”, Applied and Environmental Microbiology, 1996, 4465-4470.
Dujon, “Genome Evolution in Yeasts”, Nature, 2004, 35-44, vol. 430.
Hellinga, “Computational Protein Engineering”, Nature Structural Biology, 1998, 525-527, vol. 5.
Hespell, “Extraction and Characterization of Hemicellulose from the Corn Fiber Produced by Corn Wet-Milling Precesses”, J. Agric. food Chem., 1998, 2615-2619, vol. 46.
Hill, “DMSO-Enhanced Whole Cell Yeast Transformation”, Nucleic Acids Research, 1991, 5791, vol. 19.
Hofmann, “A Database of Membrane Spanning Protein Segments”, Konferenz der Gesellschaft fur Biologische Chemie, 1993, 166, vol. 374.
Kotter, “Isolation and Characterization of Transformant”, Current Genetics, 1990, 493-500, vol. 18.
Kruckeberg, “The Hexose Transporter Family ofSaccharomyces cerevisiae”, Arch. Microbiol., 1996, 283-292, vol. 166.
Landschulz, “The Leucine Zipper: A Hypothetical Structure . . . DNA Binding Proteins”, Science, 1988, 1759-1764, vol. 240.
Luckow, “Trends in the Development of Baculovirus Expression Vectors”, Bio/Technology, 1988, 47-55, vol. 6.
McMillan, “Arabinose Utilization b Xylose-Fermenting Yeasts and Fungi”, Applied Biochemistry and Biotechnology, 1994, 569-584, vol. 45/46.
Saitou, The Neighbor-Joining Method: A Method for Reconstructing Phylogenetic Trees, Mol. Biol. Evol . 1987, 406-425.
Sedlak, “Expression ofE. coliaraBAD Operon . . . inSaccharomyces cerevisiae”, Enzyme and Microbial Technology, 2001, 16-24.
Stambuk, “d-Xylose Transport byCandida succiphilaandKluyveromyces marxianus”, Applied Biochemistry and Biotechnology, 2003, 255-263, vol. 105-108.
Tietz, “Determination of Alcohols by Gas Chromatography”, Fundamentals of Clinical Chemistry, 1976, 1110-1111.
Van Den Burg, “Engineering an Enzyme to Resist Boiling”, Proc. Natl. Acad. Sci., 1998, 2056-2060, vol. 95.
Wahlbom, “Furfural, 5-Hydroxymethyl Furfural . . . in RecombinantSaccharomyces cerevisiae”, Biotechnology and Bioengineering, 2002, 172-178, vol. 78.
Weierstall, “Cloning and Characterization of Three Genes of the YeastPichia stipitis”, Molecular Microbiology, 1999, 871-883.
Zhang, Metabolic Engineering of a Pentose Metabolism Pathway in EthanologenicZymomonas mobilis, Science, 1995, 240-243, vol. 267.
Zhao, “Molecular Evolution by Staggered Extension Process (StEP) in Vitro Recombination”, Nature Biotechnology, 1998, 258-261, vol. 16.
Segal, “Toward Controlling Gene Expression Target Sequences”, Proc Natl. Acad. Sci., 1999, 2758-2763, vol. 96.
Kao, “Genetics of Somatic Mammalian Cells . . . in Chinese Hamster Cells”, Genetics, 1968, 1275-1281, vol. 60.
Smith, “Comparison of Biosequences”, Advances in Applied Mathematics, 1981, 482-489.
Wigler, “Transformation of Mammalian Cells with an Amplifiable Dominant-Acting Gene”, Proc. Natl. Acad. Sci, 1980, 3567-3570, vol. 77.
O'Hare, “Transformation of Mouse Fibroblasts to . . . Dihydrofolate Reductase”, Proc. Natl. Acad. Sci, 1981, 1527-1531, vol. 78.
Mulligan, “Selection for Animal Cells That Express for Xanthine-Guanine Phosphoribosyltransferase”, Proc. Natl. Acad. Sci, 1981, 2072-2076, vol. 78.
Colbere-Garapin, “A New Dominant Hybrid Selective Marker for Higher Eukaryotic Cells”, J. Mol. Biol., 1981, 1-14.
Santerre, “Expression of Prokaryotic Genes for Hygromycin . . . in Mouse L Cells”, Gene, 1984, 147-156.
Altschul, “Basic Local Alignment Search Tool”, J. Mol. Biol., 1990, 403-410.

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