KS-laminin and methods of use

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Glycoprotein – e.g. – mucins – proteoglycans – etc.

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Details

530350, 530842, 530851, 530353, C07K 1478, C07K 1447, A61K 3839, A61K 3817

Patent

active

055809600

ABSTRACT:
KS-laminin and a KS-laminin-kalinin adduct are disclosed. The molecules of the invention are useful for promoting the adhesion of keratinocytes to a substrate.

REFERENCES:
patent: 5003044 (1991-03-01), Hunter et al.
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Hunter et al., "Primary Sequence of a Motor Neuron-Selective Adhesive Site in the Synaptic Basal Protein S-Laminin" Cell, vol. 59, pp. 905-913, 1989.
Frenette et al., "Biosynthesis and Secretion of Laminin and Laminin-associated Glycoproteins by Nonmalignant and Malignant Human Keratinocytes: Comparison of Cell Lines from Primary and Secondary Tumors in the Same Patient" Cancer Research, vol. 48, pp. 5193-5202, 1988.
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