Kits useful for sequencing nucleic acids

Details Kits useful for sequencing nucleic acids Kits useful for sequencing nucleic acids

2006-12-29

2008-11-11

Riley, Jezia (Department: 1637)

Chemical apparatus and process disinfecting, deodorizing, preser

Analyzer, structured indicator, or manipulative laboratory...

Means for analyzing liquid or solid sample

C435S006120, C435S091100, C536S023100, C536S024300, C536S024330, C536S026600

Reexamination Certificate

active

07449149

ABSTRACT:
Novel linkers for linking a donor dye to an acceptor dye in an energy transfer fluorescent dye are provided. These linkers facilitate the efficient transfer of energy between a donor and acceptor dye in an energy transfer dye. One of these linkers for linking a donor dye to an acceptor dye in an energy transfer fluorescent dye has the general structure R21Z1C(O)R22R28where R21is a C1-5alkyl attached to the donor dye, C(O) is a carbonyl group, Z1is either NH, sulfur or oxygen, R22is a substituent which includes an alkene, diene, alkyne, a five and six membered ring having at least one unsaturated bond or a fused ring structure which is attached to the carbonyl carbon, and R28includes a functional group which attaches the linker to the acceptor dye.

REFERENCES:
patent: 3679358 (1972-07-01), Lohe et al.
patent: 4318846 (1982-03-01), Khanna et al.
patent: 4647675 (1987-03-01), Mayer et al.
patent: 4777128 (1988-10-01), Lippa
patent: 4855225 (1989-08-01), Fung et al.
patent: 4996143 (1991-02-01), Heller et al.
patent: 5118802 (1992-06-01), Smith et al.
patent: 5188934 (1993-02-01), Menchen et al.
patent: 5254477 (1993-10-01), Walt
patent: 5326692 (1994-07-01), Brinkley et al.
patent: 5340716 (1994-08-01), Ullman et al.
patent: 5342789 (1994-08-01), Chick et al.
patent: 5366860 (1994-11-01), Bergot et al.
patent: 5401847 (1995-03-01), Glazer et al.
patent: 5405975 (1995-04-01), Kuhn et al.
patent: 5410030 (1995-04-01), Yue et al.
patent: 5439797 (1995-08-01), Tsien et al.
patent: 5453517 (1995-09-01), Kuhn et al.
patent: 5532129 (1996-07-01), Heller
patent: 5552540 (1996-09-01), Haralambidis
patent: 5565322 (1996-10-01), Heller
patent: 5565554 (1996-10-01), Glazer et al.
patent: 5573909 (1996-11-01), Singer et al.
patent: 5582977 (1996-12-01), Yue et al.
patent: 5607834 (1997-03-01), Bagwell
patent: 5646264 (1997-07-01), Glazer et al.
patent: 5654419 (1997-08-01), Mathies et al.
patent: 5688648 (1997-11-01), Mathies et al.
patent: 5707804 (1998-01-01), Mathies et al.
patent: 5728528 (1998-03-01), Mathies et al.
patent: 5741657 (1998-04-01), Tsien et al.
patent: 5760201 (1998-06-01), Glazer et al.
patent: 5763189 (1998-06-01), Buechler et al.
patent: 5800996 (1998-09-01), Lee et al.
patent: 5824799 (1998-10-01), Buechler et al.
patent: 5843658 (1998-12-01), Uchiyama et al.
patent: 5847162 (1998-12-01), Lee et al.
patent: 5851778 (1998-12-01), Oh et al.
patent: 5853992 (1998-12-01), Glazer et al.
patent: 5863727 (1999-01-01), Lee et al.
patent: 5869255 (1999-02-01), Mathies et al.
patent: 5945283 (1999-08-01), Kwok et al.
patent: 5945526 (1999-08-01), Lee et al.
patent: 5981200 (1999-11-01), Tsien et al.
patent: 6008373 (1999-12-01), Waggoner et al.
patent: 6028190 (2000-02-01), Mathies et al.
patent: 6048982 (2000-04-01), Waggoner et al.
patent: 6291162 (2001-09-01), Tsien et al.
patent: 6335440 (2002-01-01), Lee et al.
patent: 6358684 (2002-03-01), Lee et al.
patent: 6472205 (2002-10-01), Tsien et al.
patent: 6849745 (2005-02-01), Lee et al.
patent: 7169939 (2007-01-01), Lee et al.
patent: 2007/0154924 (2007-07-01), Lee et al.
patent: 2007/0154925 (2007-07-01), Lee et al.
patent: 2007/0154926 (2007-07-01), Lee et al.
patent: 2007/0161026 (2007-07-01), Lee et al.
patent: 2007/0161027 (2007-07-01), Lee et al.
patent: 2007/0212709 (2007-09-01), Lee et al.
patent: 1243370 (1973-02-01), None
patent: 45263 (1887-11-01), None
patent: 47451 (1887-11-01), None
patent: 108347 (1898-11-01), None
patent: 2049503 (1971-04-01), None
patent: 2049527 (1971-04-01), None
patent: 3425631 (1986-01-01), None
patent: 0 201 751 (1986-11-01), None
patent: 0 229 943 (1987-07-01), None
patent: 0 299 943 (1987-07-01), None
patent: 0 252 683 (1988-01-01), None
patent: 0 601 889 (1994-06-01), None
patent: 0 747 700 (1996-12-01), None
patent: 0 967 219 (1999-12-01), None
patent: 1273454 (1972-05-01), None
patent: 1286885 (1972-08-01), None
patent: 2 301 833 (1996-12-01), None
patent: 0410735 (1992-04-01), None
patent: 04107559 (1992-09-01), None
patent: 5-60698 (1993-03-01), None
patent: WO 89/03041 (1989-04-01), None
patent: WO 91/03476 (1991-03-01), None
patent: WO 91/05060 (1991-04-01), None
patent: WO 91/07507 (1991-05-01), None
patent: WO 92/00388 (1992-01-01), None
patent: WO 93/0648204 (1993-04-01), None
patent: WO 93/09128 (1993-05-01), None
patent: WO 93/13224 (1993-07-01), None
patent: WO 93/23492 (1993-11-01), None
patent: WO 94/05688 (1994-03-01), None
patent: WO 94/17397 (1994-08-01), None
patent: WO 94/28166 (1994-12-01), None
patent: WO 95/21266 (1995-08-01), None
patent: WO 96/04405 (1996-02-01), None
patent: WO 96/30540 (1996-10-01), None
patent: WO 96/41166 (1996-12-01), None
patent: WO 97/11084 (1997-03-01), None
patent: WO 99/02544 (1999-01-01), None
Abdel-Mottaleb, M.S.A., et al., “Photophysics and dynamics of cournarin laser dyes and their analytical implications,”Proc.-Indian Acad. Scie. Chem. Sci., 1992, 104: 185-196.
Anton, J.A., et al., “Transfer of Excitation Energy Between Porphyrin Centers of a Covalently-Linked Dimer,”Photochemistry and Photobiology, 1978, 28: 235-242.
Asseline, U., et al., “Oligonucleotides Covalently Linked to Intercalating Dyes as Base Sequence-Specific Ligands: Influence of Dye Attachment Site,”EMBO Journal, 1984, 3: 795-800.
Benson, S., et al., “Fluorescence Energy-Transfer Cyanine Heterodimers with High Affinity for Double-Stranded DNA-1. Synthesis and Spectroscopic Properties,”Analytical Biochemistry, Jun. 1995, pp. 247-255.
Benson, S.C., et al., “Heterodimeric DNA-binding dyes designed for energy transfer: stability and applications of the DNA complexes,”Nucleic Acid Research, Nov. 1993, 21: 5720-5726.
Benson, S.C., et al., “Heterodimeric DNA-binding dyes designed for energy transfer: synthesis and spectroscopic properties,”Nucleic Acids Research, Nov. 1993, 21: 5727-5735.
Bergstrom, D., et al., “C-5 substituted Nucleoside Analogs,”SYNLETT, 1992, 3: 179-188.
Bothner, A.A., et al., “Molecular Dynamics of covalently linked multi-porphyrin arrays,”J. Phys. Chem., 1996, 100: 17551-17557.
Brumbaugh, J., et al., “Continuous On-Line DNA Sequencing Using Oligonucleotide Primers with Multiple Fluorophores,”Proc. Natl. Acad. Sci. USA, 1988, 85: 5610-5614.
Cardullo, R.A., et al., “Detection of nucleic acid hybridization by nonradiative fluorescence resonance energy transfer,”Proc. Natl. Acad. Sci. USA, Dec. 1988, 85(23): 8790-8794.
Chiu, H.C., et al., “Electronic energy transfer between tyrosine and tryptophan in the peptides Tyr-(Pro)n-Tyr,”Biopolymers, 1977, 16: 277.
Clegg, R.M., “Fluorescence resonance energy transfer and nucleic acids,”Method Enzymol, 1992, 211: 353-388.
Conrad, R.H., et al., “Intramolecular transfer of excitation from tryptophan to 1-dimethylaminonapthalene-5-sulfonamide in a series of model compounds,”Biochemistry, 1968, 7: 777.
Cooper, J., et al., “Analysis of Fluorescence Energy Transfer in Duplex and Branched DNA Molecules,”Biochemistry, 1990, 29(39): 9261-9268.
Delaney, J.K., et al., “Electron tunneling in a cofacial zinc porphyrin-quinone cage molecule: Novel Temperature and solvent dependent,”J. Am. Chem. Soc., 1990, 112(3): 957-963.
Dirks, G., et al., “Light absorption and energy transfer in polyene-porphyrin esters,”Photochemistry and Photobiology, 1980, 32: 277-280.
Drake, J.M., et al., “Chemical and Biological Microstructures as Probed by Dynamic Processes,”Science, Mar. 1991, 251: 1574-1579.
Effenberger, F., et al., “Synthesis and optical properties of terminally substituted conjugated polyenes,”Agnew. Chem. Int. Ed. Engl., 1988, 27(2): 281-284.
Florkin, M., et al., “Mechanism of energy transfer,”Comprehensive Biochemistry, 1967, 22: 61.
Forster, T., “Intermolecular Energy Migration and fluorescence,”Ann. Physik(Leipzig), 1948, 2: 55.
Gust, D., et al., “A synthetic system mimicking the energy transfer and charge separation of natural photosynthesis,

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