Kit used for fabricating an integrated biomolecule sensor

Details Kit used for fabricating an integrated biomolecule sensor Kit used for fabricating an integrated biomolecule sensor

2005-02-15

2005-02-15

Redding, David A. (Department: 1744)

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

C435S288700, C435S810000

Reexamination Certificate

active

06855541

ABSTRACT:
This invention provides a kit used for fabricating an integrated biomolecule sensor. The kit includes an optical fiber bundle unit, which holds the proximal ends of the plurality of optical fibers together with the end-face arranged substantially in the same plane and oriented substantially in the same direction, a plate with wells for holding solutions containing probe polymers with different base sequences, and an auxiliary plate having holes, which corresponds to the wells of the plate respectively. According to this invention, researchers and other people can easily fabricate the integrated biomolecule under individual requirements without need of expensive equipment.

REFERENCES:
patent: 6023540 (2000-02-01), Walt et al.
patent: 6406845 (2002-06-01), Walt et al.
patent: 20030143725 (2003-07-01), Chen et al.
patent: 5-28500 (1993-11-01), None
patent: WO 9727326 (1997-07-01), None
U.S. Provisional Appl. No. 60/216,265, filed Jul. 2000, Chen et al.*
Patent Abstracts of Japan, Publication No. 05-285000, Publication Date Nov. 2, 1993, 2 pages.
Lee, Myoyong and Walt, David R.; “A Fiber-Optic Microarray Biosensor Using Aptamers as Receptors”; Max Tishler Laboratory for Organic Chemistry, Department of Chemistry, Tufts University, Medford, Massachusetts, Feb. 16, 2000; pp. 142-146.
Walt, David R; “Techview: Molecular Biology, Bead-Based Fiber-Optic Arrays”; Science vol. 287, Jan. 21, 2000, pp. 451-452.
Steemers, Frank J., Ferguson, Jane, A., Walt, David R.; “Screening Unlabeled DNA Targets with Randomly Ordered Fiber-Optic Gene Arrays”; Nature Biotechnology vol. 18; Jan. 2000; pp. 91-94.
Michael, Karri L., Taylor, Laura C., Schultz, Sandra, L., Walt, David R.; “Randomly Ordered Addressable High-Density Optical Sensor Arrays”; Analytical Chemistry, vol. 70, No. 7, Apr. 1, 1998, pp. 1242-1248.
Ferguson, Jane, A., Boles, T. Christian, Adams, Christopher, P., Walt, David, R.; “A Fiber-Optic DNA Biosensor Microarray for the Analysis of Gene Expression” Nature Diotechnology, vol. 14, Dec. 1996, pp. 1681-1684.

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