Kit for the rapid preparation of .sup.99m Tc red blood cells

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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2523011R, 232585R, A61K 2900, A61K 4300

Patent

active

039884295

ABSTRACT:
A method and sample kit for the preparation of .sup.99m Tc-labeled red blood cells in a closed, sterile system. A partially evacuated tube, containing a freeze-dried stannous citrate formulation with heparin as an anticoagulant, allows whole blood to be automatically drawn from the patient. The radioisotope is added at the end of the labeling sequence to minimize operator exposure. Consistent 97% yields in 20 minutes are obtained with small blood samples. Freeze-dried kits have remained stable after five months.

REFERENCES:
patent: 3725295 (1973-04-01), Eckelman et al.
Smith, International Journal of Applied Radiation and Isotopes, vol. 25, No. 3, Mar., 1974, pp. 137-139.
American Journal of Roentgenology, Radium Therapy and Nuclear Medicine, vol. 118, No. 4, Aug., 1973, pp. 861-864.

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