Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Glycoprotein – e.g. – mucins – proteoglycans – etc.
Patent
1989-05-17
1991-01-15
Kepplinger, Esther L.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Glycoprotein, e.g., mucins, proteoglycans, etc.
424 88, 424558, 435810, 436808, 530412, 530417, 530422, 530806, 530835, C07K 1514, C07K 300, A61K 3900, A61K 3512
Patent
active
049855425
ABSTRACT:
Purified glomerular proteoglycans are used as a basis for a diagnostic test for glomerulonephritis in humans involving an immunological reaction between the purified proteoglycans and patient area. A new method for purification of glomeruli proteoglycan antigens is described using guanidine extraction.
REFERENCES:
Kefalides, Connective Tissue Res., 1:3-13, "The Chemistry of Antigenic Components Isolated From Glomerular Basement Membrane", (1972).
Kanwar et al., Chemical Abstracts 95: 110476d, 245, "Partial Characterization of Newly Synthesized Proleoglycans Isolated From the Glomerular Basement Membrane", (1981).
Kanwar, Y., et al. (1981) The Journal of Cell Biology, vol. 90, pp. 527-532.
Damle Shridhar P.
Fillit Howard
Gregory John D.
Zabriskie John
Hoffer Florina B.
Kepplinger Esther L.
The Rockefeller University
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