Kit for the determination and diagnosis of non-goodpasture glome

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Glycoprotein – e.g. – mucins – proteoglycans – etc.

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424 88, 424558, 435810, 436808, 530412, 530417, 530422, 530806, 530835, C07K 1514, C07K 300, A61K 3900, A61K 3512

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049855425

ABSTRACT:
Purified glomerular proteoglycans are used as a basis for a diagnostic test for glomerulonephritis in humans involving an immunological reaction between the purified proteoglycans and patient area. A new method for purification of glomeruli proteoglycan antigens is described using guanidine extraction.

REFERENCES:
Kefalides, Connective Tissue Res., 1:3-13, "The Chemistry of Antigenic Components Isolated From Glomerular Basement Membrane", (1972).
Kanwar et al., Chemical Abstracts 95: 110476d, 245, "Partial Characterization of Newly Synthesized Proleoglycans Isolated From the Glomerular Basement Membrane", (1981).
Kanwar, Y., et al. (1981) The Journal of Cell Biology, vol. 90, pp. 527-532.

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