Kit for preparing Tc (III)-99m myocardial imaging agents that ar

Details Kit for preparing Tc (III)-99m myocardial imaging agents that ar Kit for preparing Tc (III)-99m myocardial imaging agents that ar

1990-01-11

1990-09-18

Maples, John B.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

534 14, 206569, A61K 4902, B65D 6900

Patent

active

049577280

ABSTRACT:
A myocardial imaging agent for humans is a technetium(III) complex ligated in the planar positions by a tetradentate ligand such as (acac).sub.2 en and in the axial positions by an ether containing phosphine ligand such as tris(3-methoxy-1-propyl)-phosphine. The agent exhibits extremely rapid blood clearance after injection into a human and has a sufficiently high heart/liver and heart/lung ratios to provide effecitve myocardial images. A kit for preparing the above myocardial agent is disclosed.

REFERENCES:
patent: 4795626 (1989-01-01), Deutsch et al.
patent: 4917879 (1990-04-01), Deutsch et al.

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