Kit for detection of islet amyloid polypeptide (IAPP)

Details Kit for detection of islet amyloid polypeptide (IAPP) Kit for detection of islet amyloid polypeptide (IAPP)

1994-01-18

1995-06-13

Saunders, David

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

436501, 436533, 436548, 435 792, 435 794, 435 795, 435975, 5303871, 5303879, 53038824, G01N 3353, C07K 1626, C07K 1400, C07K 1462

Patent

active

054242215

ABSTRACT:
This invention is directed to kits for the detection of human islet amyloid polypeptide (IAPP) comprising (a) purified preparations of antibodies which react specifically with insulin or calcitonin gene-related peptides and (b) a preselected amount of human islet amyloid polypeptide which is essentially free of islet amyloid, which polypeptide is one subunit of islet amyloid and which is prepared by depolymerizing human islet amyloid; or a preselected amount of human islet amyloid polypeptide which is essentially free of islet amyloid and has the amino acid sequence: lys-cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Se r-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr.

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